Induction of Dermal Fibroblasts into Dermal Papilla Cell-Like Cells in Hydrogel Microcapsules for Enhanced Hair Follicle Regeneration

    December 2020 in “ Applied Materials Today
    Bai-Song Xie, Mengting Chen, Pinghui Ding, Lei Lei, Xing Zhang, Dan Zhu, Yujian Zou, Zhili Deng, Guoming Sun, Ji Li, Hemin Nie
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    TLDR Hydrogel microcapsules help create cells that boost hair growth.
    A 2020 study found that hydrogel microcapsules can transform dermal fibroblasts into dermal papilla cell-like cells, which can potentially enhance hair follicle regeneration and stimulate hair growth. The induced cells exhibited improved hair follicle regeneration potential through the Wnt signaling pathway. This technique could provide a safe and abundant source of dermal papilla cells for hair regeneration therapies.
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