Effects of Oral Minoxidil on Serum VEGF and Hair Regrowth in Androgenetic Alopecia

    Ahmed Abdulhussein Kawen
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    TLDR Oral minoxidil boosts hair growth and reduces shedding in androgenetic alopecia.
    This study investigated the effects of oral minoxidil on serum VEGF levels and hair regrowth in androgenetic alopecia, involving 50 participants split into two groups: oral minoxidil (1 mg/day) and control. After 12 weeks, the minoxidil group showed a significant increase in VEGF levels compared to the control (217.88 ± 22.65 pg/ml vs. 142.81 ± 23.14 pg/ml, p < 0.0001). Hair count and diameter improved significantly, while shedding and pull test results decreased. Positive correlations were found between VEGF and hair count, and negative correlations with shedding. The study concludes that oral minoxidil enhances VEGF levels, promoting hair growth and reducing shedding, with VEGF as a potential biomarker for treatment effectiveness in AGA.
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