Utilization of Response Surface Design for Development and Optimization of Rosuvastatin Calcium-Loaded Nano-Squarticles for Hair Growth Stimulating VEGF and IGF Production: In Vitro and In Vivo Evaluation

September 2023 in “ Drug development and industrial pharmacy ”

Mervat S. Ibrahim, Nihal Mohamed Elmahdy Elsayyad, Abeer Salama, Shereen H. Noshi

rosuvastatin calcium nano-squarticles VEGF IGF hair growth in-vitro in-vivo

TLDR The optimized formula promotes significant hair growth and could be a viable hair loss treatment.

The study focused on developing and optimizing rosuvastatin calcium-loaded nano-squarticles to stimulate hair growth by enhancing the production of VEGF and IGF. Using response surface design, the researchers conducted both in-vitro and in-vivo evaluations. The findings demonstrated that the optimized nano-squarticles significantly promoted hair growth, suggesting their potential as an effective treatment for hair loss.

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