Single-Cell Profiling Reveals a Potent Role of Quercetin in Promoting Hair Regeneration

    November 2022 in “ Protein & Cell ”
    Qian Zhao, Yandong Zheng, Dongxin Zhao … Jing Qu
    Studysummary In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.
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    Research cited in this study 34

    1. Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis Cell Stem Cell · 2021
    2. Hair Follicle Stem Cells as a Skin-Organizing Signaling Center During Adult Homeostasis The EMBO Journal · 2021
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    10. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration Cell Stem Cell · 2018
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    12. Aging in Hair Follicle Stem Cells and Niche Microenvironment The Journal of Dermatology · 2017
    13. Global Gene Expression and Comparison Between Multiple Populations in the Mouse Epidermis Stem Cell Research · 2016
    14. Foxc1 Reinforces Quiescence in Self-Renewing Hair Follicle Stem Cells Science · 2016
    15. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
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    19. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    20. Defining Dermal Adipose Tissue Experimental Dermatology · 2014
    21. Exposure to Gamma-Rays at the Telogen Phase of the Hair Cycle Inhibits Hair Follicle Regeneration at the Anagen Phase in Mice International Journal of Radiation Biology · 2013
    22. Hairless Down-Regulates Expression of Msx2 and Its Related Target Genes in Hair Follicles Journal of dermatological science · 2013
    23. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
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    25. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012
    26. Prevention and Treatment of Alopecia Areata with Quercetin in the C3H/HeJ Mouse Model Cell stress & chaperones · 2011
    27. Hoxc13 And The Development Of Hair Follicle Hereditas (Beijing) · 2010
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    29. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008
    30. Scratching the Surface of Skin Development Nature · 2007
    31. The Hair Cycle Journal of Cell Science · 2006
    32. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002
    33. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    34. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999

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