14 citations
,
February 2021 in “Journal of Dermatological Treatment” 10% minoxidil solution better promotes hair growth and reduces hair loss without significant side effects.
14 citations
,
November 2020 in “Dermatologic Therapy” Oral minoxidil improves hair density in women with androgenetic alopecia, with mild side effects.
24 citations
,
September 2020 in “Dermatology and therapy” Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.
19 citations
,
May 2020 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil improves hair growth in male hair loss.
16 citations
,
May 2020 in “Journal of The European Academy of Dermatology and Venereology” Sublingual minoxidil effectively treats hair loss with mild side effects.
12 citations
,
February 2020 in “Skin appendage disorders” Low-dose oral minoxidil effectively treats female hair loss with good safety.
11 citations
,
March 2019 in “International Journal of Trichology”
54 citations
,
December 2018 in “Journal of The European Academy of Dermatology and Venereology” Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.
36 citations
,
September 2018 in “Dermatologic Therapy” Oral minoxidil helps hair growth, is cost-effective, and mostly well-tolerated.
27 citations
,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
19 citations
,
April 2018 in “Journal of Pharmaceutical Sciences” A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.
145 citations
,
January 2018 in “Journal of The European Academy of Dermatology and Venereology” Use minoxidil for hair loss treatment; assess results after 6 months.
80 citations
,
January 2018 in “International Journal of Dermatology” Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.
40 citations
,
September 2017 in “F1000Research” Oral minoxidil effectively reduces hair shedding in women with CTE, with no major side effects.
178 citations
,
July 2017 in “Journal of The American Academy of Dermatology” Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
12 citations
,
June 2017 in “Cell Cycle” Minoxidil foam helps hair growth by increasing good proteins and decreasing bad pathways in men with hair loss.
32 citations
,
February 2017 in “Aaps Pharmscitech” Nanostructured lipid carriers improve minoxidil delivery for hair loss treatment.
33 citations
,
January 2017 in “European Journal of Pharmaceutical Sciences” Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
36 citations
,
November 2016 in “Australasian Journal of Dermatology” Low dose oral minoxidil helps regrow hair in permanent chemotherapy-induced alopecia.
24 citations
,
October 2016 in “Oncotarget” Finasteride has a higher risk of reproductive side effects than minoxidil.
20 citations
,
July 2016 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil foam promotes hair growth and reduces hair loss safely in men.
13 citations
,
June 2016 in “Dermatologic Therapy” Minoxidil works better when applied on a damp scalp than a dry one.
19 citations
,
June 2015 in “British Journal of Dermatology” Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.
19 citations
,
March 2015 in “Skin Pharmacology and Physiology” Minoxidil foam effectively promotes hair growth and reduces hair loss in men.
24 citations
,
April 2014 in “Oncotarget” Minoxidil can reduce functions related to androgen receptors.
5 citations
,
March 2013 in “Journal of cosmetic and laser therapy” Laser treatment successfully removed unwanted facial hair caused by minoxidil.
152 citations
,
May 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
205 citations
,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
100 citations
,
December 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
6 citations
,
December 2011 in “Archives de pédiatrie” Minoxidil ingestion can cause severe heart issues and requires careful medical monitoring.
88 citations
,
June 2011 in “Journal of Dermatological Science” Minoxidil helps hair growth by activating the β-catenin pathway.
74 citations
,
November 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Minoxidil foam enters hair follicles and skin for hair growth.
39 citations
,
June 2010 in “International Journal of Pharmaceutics” Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.
30 citations
,
May 2010 in “British Journal of Dermatology” Intermediate hair follicles are a better model for studying hair growth and testing hair loss treatments.
55 citations
,
February 2010 in “Journal of Pharmaceutical Sciences” Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.
25 citations
,
January 2010 in “International Journal of Pharmaceutics” Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
128 citations
,
October 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
211 citations
,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
4 citations
,
January 2009 in “International journal of trichology”
212 citations
,
October 2008 in “Journal of The American Academy of Dermatology” Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
102 citations
,
June 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
142 citations
,
November 2007 in “Journal of The American Academy of Dermatology” New 5% minoxidil foam effectively promotes hair growth and is safe for use.
65 citations
,
August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
23 citations
,
February 2007 in “Journal of Dermatological Science” Ethosomal minoxidil improves hair growth by penetrating deeper into skin and shortening hair cycle.
85 citations
,
February 2007 in “Journal of Drug Targeting” Liposomes better deliver minoxidil for hair loss treatment than niosomes.
14 citations
,
January 2007 in “Journal of Dermatological Treatment” Minoxidil solution had low effect, causing 99% to stop using it.
43 citations
,
January 2007 in “American Journal of Clinical Dermatology” Combined minoxidil and tretinoin solution works as well as regular minoxidil for male hair loss.
27 citations
,
November 2005 in “Archives of Dermatological Research” Choosing hair follicles at the same growth stage leads to more consistent hair growth experiments.
35 citations
,
April 2005 in “Journal of Investigative Dermatology” Potassium channel openers like minoxidil help hair grow by acting on hair follicles.
316 citations
,
July 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
219 citations
,
April 2004 in “Journal of The American Academy of Dermatology” 5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
149 citations
,
April 2004 in “Journal of Dermatological Science” Minoxidil boosts hair growth by increasing cell production and survival.
34 citations
,
March 2004 in “Journal of Liposome Research” Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
397 citations
,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
29 citations
,
December 2003 in “Teratology” Minoxidil use during pregnancy may cause fetal harm.
30 citations
,
October 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
14 citations
,
September 2003 in “Archives of Dermatology” Finasteride may not stop severe hair loss after stopping minoxidil.
26 citations
,
July 2003 in “Journal of Cutaneous Medicine and Surgery” Minoxidil solution safely and effectively treats hair loss.
63 citations
,
May 2003 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil use increases facial hair growth in females, more in older users.
24 citations
,
January 2003 in “Drug Delivery” Minoxidil-containing vesicles improve hair growth.
269 citations
,
September 2002 in “Journal of The American Academy of Dermatology” 5% minoxidil works better for hair growth and density, with minor irritation.
149 citations
,
June 2002 in “British Journal of Dermatology” Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.
17 citations
,
April 2002 in “Contact Dermatitis” Minoxidil 5% caused skin discoloration in a man using it for hair loss.
123 citations
,
February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
83 citations
,
December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
115 citations
,
November 1999 in “Journal of The American Academy of Dermatology” Minoxidil increases hair weight and count temporarily in men with hair loss.
370 citations
,
September 1999 in “The New England Journal of Medicine” Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
34 citations
,
February 1999 in “Journal of Dermatological Science” Minoxidil boosts enzymes that help hair growth.
179 citations
,
September 1998 in “BMJ” Hair loss in men is common, treatable, but not curable.
118 citations
,
April 1998 in “Dermatologic Clinics” Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
192 citations
,
March 1998 in “British Journal of Dermatology” Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.
59 citations
,
February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
34 citations
,
July 1997 in “Skin Pharmacology and Physiology” Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
81 citations
,
February 1997 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by activating PGHS-1.
44 citations
,
January 1997 in “British Journal of Dermatology”
82 citations
,
March 1994 in “Archives of Dermatology” 2% topical minoxidil effectively treats female hair loss with minimal side effects.
13 citations
,
October 1993 in “International Journal of Dermatology” Minoxidil effectively promotes hair regrowth in younger patients with small balding areas.
58 citations
,
October 1993 in “International Journal of Dermatology” Minoxidil helps hair growth and reduces shedding in women.
309 citations
,
May 1993 in “Journal of The American Academy of Dermatology” Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
53 citations
,
January 1993 in “Biochemical Pharmacology” Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.
24 citations
,
January 1993 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, works better for women, and requires consistent use.
43 citations
,
November 1992 in “International Journal of Dermatology” Minoxidil 2% effectively treats female hair loss, promoting growth and density.
15 citations
,
September 1992 in “The Lancet” Stopping minoxidil caused significant hair loss, but regrowth occurred after resuming use.
27 citations
,
April 1992 in “Biochemical Journal” Minoxidil reduces lysine hydroxylase in skin cells.
14 citations
,
September 1991 in “Journal of Investigative Dermatology” Minoxidil slows down keratinocyte growth without being toxic.
85 citations
,
December 1990 in “Journal of Investigative Dermatology” Minoxidil promotes hair growth in women with early-stage alopecia.
166 citations
,
November 1990 in “Journal of Investigative Dermatology” Minoxidil sulfate stimulates hair growth.
25 citations
,
June 1990 in “Journal of Pharmaceutical Sciences” Longer contact time increases minoxidil absorption, but doesn't affect metabolism.
70 citations
,
April 1990 in “Journal of The American Academy of Dermatology” Minoxidil treatment increased hair growth for up to 5 years, requiring twice daily application.
30 citations
,
April 1990 in “Clinical Pharmacology & Therapeutics” Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.
19 citations
,
September 1989 in “Journal of The American Academy of Dermatology” Minoxidil treatment may cause hair loss.
25 citations
,
February 1989 in “The Journal of Clinical Pharmacology” This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
31 citations
,
January 1989 in “Clinical and Experimental Dermatology” The study tested a hair treatment and found it can help grow hair, but won't stop baldness. It's safe and works well, but needs more testing.
38 citations
,
October 1988 in “Clinics in Dermatology” Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.
45 citations
,
October 1988 in “British Journal of Clinical Pharmacology” Using topical minoxidil for baldness can cause heart problems, especially in those with heart disease.
23 citations
,
March 1988 in “Biochemical Pharmacology” Minoxidil stops cells from making prostacyclin, which may help with hair growth. More research is needed.
34 citations
,
November 1987 in “Archives of Dermatology” Oral minoxidil helps hair regrowth in 80% of alopecia patients, but only 18% see cosmetic improvement.
25 citations
,
November 1987 in “British Journal of Dermatology” Minoxidil didn't increase scalp blood flow for hair growth, but hexyl nicotinate did.
20 citations
,
November 1987 in “Archives of Dermatology” The document concludes that topical minoxidil therapy is safe and effective in promoting hair growth for male pattern baldness.
57 citations
,
July 1987 in “Journal of The American Academy of Dermatology” Stopping minoxidil treatment resumes balding; continuous use needed for results.