Oleic Acid Nanovesicles of Minoxidil for Enhanced Follicular Delivery

September 2018 in “ Medicines ”

Pawan Kumar, Shailendra Singh, Vandana Handa, Himanshu Kathuria

oleic acid nanovesicles minoxidil follicular delivery alopecia areata drug absorption hair follicles OAV gel drug deposition skin slow release Rogaine

TLDR Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.

This document is a collection of summaries of a scientific paper titled "Oleic Acid Nanovesicles of Minoxidil for Enhanced Follicular Delivery" from 2018. The study explores the use of oleic acid nanovesicles (OAVs) as a delivery system for minoxidil to enhance drug absorption into hair follicles for the treatment of alopecia areata. The results showed that the OAV gel had a higher drug deposition in the skin and hair follicles compared to the lotion, and the drug was released slowly over time. The study suggests that OAVs could be a promising delivery system for the treatment of alopecia areata.

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Research cited in this study

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Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

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Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.

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