TLDR This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
This document summarizes various studies that examined the pharmacokinetics of minoxidil in healthy volunteers. The studies found that minoxidil is quickly absorbed and eliminated from the body, with a half-life of around 4 hours. Higher doses of minoxidil led to higher levels in the blood and longer times for the body to eliminate it. The drug had little effect on blood pressure in people with normal blood pressure, but higher doses did affect pulse rate. The studies provide important information for the safe and effective use of minoxidil in treating hair loss.
96 citations,
October 1981 in “Drugs” Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
57 citations,
January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil treats high blood pressure and side effects can be managed.
21 citations,
October 1978 in “The Journal of Clinical Pharmacology” 
21 citations,
September 1977 in “Journal of Pharmaceutical Sciences” Minoxidil levels measured in human blood.
90 citations,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
January 2023 in “Skin appendage disorders” Low-dose oral minoxidil may help treat hair loss but is not FDA-approved and can cause side effects like unwanted hair growth and heart issues.
1 citations,
July 2024 in “Journal of Cosmetic Dermatology” Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.
May 2023 in “International Journal of Trichology” Low-dose oral Minoxidil is an effective treatment for hair loss with minimal serious side effects.
43 citations,
February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
4 citations,
September 2006 in “European Journal of Clinical Pharmacology” Finasteride doesn't affect omeprazole metabolism in Japanese people.
