Characterization and Management of Adverse Events of Low-Dose Oral Minoxidil Treatment for Alopecia: A Narrative Review

    March 2025 in “ Journal of Clinical Medicine ”
    Juan ­Jimenez‐Cauhe, Kristen I. Lo Sicco, Jerry Shapiro … Sergio Vañó‐Galván
    Studysummary This study reviewed adverse events associated with low-dose oral minoxidil for treating alopecia, finding hypertrichosis and fluid retention as common, typically manageable side effects without needing treatment discontinuation.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 50

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    6. Oral Minoxidil And The Exacerbation Of Alcohol Hangover Symptoms International Journal of Dermatology · 2024
    7. Combating Dread Shed: The Impact of Overlapping Topical and Oral Minoxidil on Temporary Hair Shedding During Oral Minoxidil Initiation JAAD International · 2024
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    21. Pericardial, Pleural Effusion and Anasarca: A Rare Complication of Low-Dose Oral Minoxidil for Hair Loss JAAD case reports · 2022
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    23. Morning Periorbital Edema Due to Low-Dose Oral Minoxidil Actas Dermo-Sifiliográficas · 2022
    24. Comment on Bicalutamide Improves Minoxidil-Induced Hypertrichosis in Female Pattern Hair Loss: A Retrospective Review of 35 Patients Journal of The American Academy of Dermatology · 2022
    25. Serious Adverse Effects From Compounding Errors With Low-Dose Oral Minoxidil for Alopecia Treatment Actas Dermo-Sifiliográficas · 2022
    26. There Is a Positive Dose-Dependent Association Between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings From a Systematic Review With Meta-Regression Analyses Skin appendage disorders · 2022
    27. Bicalutamide Improves Minoxidil-Induced Hypertrichosis in Female Pattern Hair Loss: A Retrospective Review of 35 Patients Journal of The American Academy of Dermatology · 2021
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    32. Combination Oral Minoxidil and Spironolactone for the Treatment of Androgenetic Alopecia in Adolescent Girls Journal of The American Academy of Dermatology · 2020
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    38. Characterization and Management of Hypertrichosis Induced by Low-Dose Oral Minoxidil in the Treatment of Hair Loss Journal of The American Academy of Dermatology · 2020
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    44. Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension Journal of Clinical Hypertension · 2004
    45. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    46. Causes and Management of Hypertrichosis American Journal of Clinical Dermatology · 2002
    47. Spironolactone Therapy in Hypertrichosis European journal of endocrinology · 1996
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    50. Pericardial Disorders During Open-Label Study of 1,869 Severely Hypertensive Patients Treated with Minoxidil Journal of Cardiovascular Pharmacology · 1980

    Related research 7

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    2. Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes Dermatologic Therapy · 2019
    3. The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years Italian journal of dermatology and venereology · 2018
    4. Comparative Study Between 2% Minoxidil Topical Spray vs. Intradermal Injection for Treatment of Androgenetic Alopecia in Female Patients: A Controlled, 4-Month Randomized Trial 2010
    5. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    6. Androgenetic Alopecia: Treatment Results with Topical Minoxidil Journal of The American Academy of Dermatology · 1987
    7. Topical Minoxidil Therapy and Hair Regrowth Archives of Dermatology · 1985