Morning Periorbital Edema Due to Low-Dose Oral Minoxidil

April 2022 in “ Actas Dermo-Sifiliográficas ”

J.F. Mir-Bonafé, Marc Mir-Bonafé, Eduardo Rozas-Muñoz, J.M. Mir-Bonafé

minoxidil oral minoxidil androgenetic alopecia periorbital edema Rogaine

Studysummary This study describes two cases of morning periorbital edema associated with low-dose oral minoxidil for androgenic alopecia, an effect infrequently reported in the literature. Our plain-language summary of this paper — not a Tressless recommendation.

The document discussed two cases of morning periorbital edema associated with low-dose oral minoxidil, a treatment for androgenetic alopecia. The first case involved a 40-year-old man who developed eyelid swelling after four weeks on 5 mg/day, which resolved after reducing the dose to 3 mg/day. The second case was a 37-year-old woman who experienced similar symptoms after two weeks on 1 mg/day, which resolved after discontinuing the drug for 12 weeks and later reintroducing it at 0.5 mg/day. Although periorbital edema was rare, occurring in about 0.3% of cases, it was important to recognize this effect, which typically resolved spontaneously and was not severe enough to necessitate stopping the medication.

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5 / 5 results

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