Oral Minoxidil 7.5 mg for Hair Loss Increases Heart Rate with No Change in Blood Pressure in 24-Hour Holter and 24-Hour Ambulatory Blood Pressure Monitoring

    May 2024 in “ Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia ”
    Baltazar Dias Sanabria, Yuri Chiarelli Perdomo, Hélio Amante Miot, Paulo Müller Ramos
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    TLDR Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.
    A study involving 11 adult males with androgenetic alopecia (AGA) assessed the cardiovascular effects of increasing oral minoxidil dosage from 5 mg/day to 7.5 mg/day over 6 weeks. Using 24-hour Holter monitoring and ambulatory blood pressure monitoring (ABPM), the study found a mild increase in heart rate but no significant changes in blood pressure. Despite the small sample size, the results suggest that while 7.5 mg/day of minoxidil is well tolerated, doses above 5 mg/day should be used cautiously and increased gradually due to potential cardiovascular risks.
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