There Is a Positive Dose-Dependent Association Between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings From a Systematic Review With Meta-Regression Analyses

    January 2022 in “ Skin appendage disorders ”
    Anik Gupta, Deanna Hall, Mesbah Uddin Talukder, Mary A Bamimore
    Studysummary This study found that for people with androgenetic alopecia, increasing the dosage of low-dose oral minoxidil is associated with improvements in hair diameter and density, but also raises the risk of hypertrichosis and cardiovascular adverse events.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 22

    1. Relative Efficacy of Minoxidil and the 5-Alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients JAMA Dermatology · 2022
    2. Hair Are the Rankings—5-Alpha Reductase Inhibitors and Minoxidil in Male Androgenetic Alopecia JAMA Dermatology · 2022
    3. Natural Products for Male Androgenetic Alopecia Dermatologic Therapy · 2022
    4. A Randomized Clinical Trial on Therapeutic Effects of 0.25 mg Oral Minoxidil Tablets on Treatment of Female Pattern Hair Loss Dermatologic Therapy · 2021
    5. Finasteride for Hair Loss: A Review Journal of Dermatological Treatment · 2021
    6. Minoxidil: A Comprehensive Review Journal of Dermatological Treatment · 2021
    7. Review of Oral Minoxidil as Treatment of Hair Disorders: In Search of the Perfect Dose 2021
    8. Coming Full Circle (Almost): Low Dose Oral Minoxidil for Alopecia Journal of The American Academy of Dermatology · 2021
    9. Side Effects of Low-Dose Oral Minoxidil for Treating Alopecia Journal of The American Academy of Dermatology · 2021
    10. A Case of Contact Allergic Dermatitis to Topical Minoxidil Cureus · 2021
    11. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    12. Efficacy and Safety of Oral Minoxidil in Female Androgenetic Alopecia Dermatologic Therapy · 2020
    13. Safety of Low-Dose Oral Minoxidil Treatment for Hair Loss: A Systematic Review and Pooled Analysis of Individual Patient Data Dermatologic Therapy · 2020
    14. Low-Dose Oral Minoxidil as Treatment for Non-Scarring Alopecia: A Systematic Review International Journal of Dermatology · 2020
    15. Efficacy and Safety of Very-Low-Dose Oral Minoxidil 1.25 mg in Male Androgenetic Alopecia Journal of The American Academy of Dermatology · 2020
    16. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality Journal of Dermatological Treatment · 2020
    17. Very-Low-Dose Oral Minoxidil in Male Androgenetic Alopecia: A Study with Quantitative Trichoscopic Documentation Journal of The American Academy of Dermatology · 2019
    18. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    19. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    20. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    21. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    22. Minoxidil: A Review of Its Pharmacological Properties and Therapeutic Use Drugs · 1981

    Related research 7

    1. There Is a Positive Dose-Dependent Association Between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings From a Systematic Review With Meta-Regression Analyses Skin appendage disorders · 2022
    2. Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review Cosmoderma · 2021
    3. Minoxidil-Induced Hypertrichosis in a Child with Alopecia Areata Indian Dermatology Online Journal · 2017
    4. Infantile Generalized Hypertrichosis Caused by Topical Minoxidil Anais Brasileiros de Dermatologia · 2016
    5. Long-Pulsed Nd:YAG Laser in the Treatment of Facial Hypertrichosis During Topical Minoxidil Therapy Journal of cosmetic and laser therapy · 2013
    6. Generalized Hypertrichosis After Treatment With Topical Minoxidil Clinical and Experimental Dermatology · 1994
    7. Hypertrichosis Due to Minoxidil British Journal of Dermatology · 1979