TLDR Minoxidil 5% caused skin discoloration in a man using it for hair loss.
A 57-year-old man with androgenetic alopecia was treated with topical minoxidil 5% for 2 years and developed hyperpigmentation on his waist and neck towards the end of the treatment. Patch tests with the European standard series and a textile dye and finishes series were negative, but a patch test with topical minoxidil 5% was positive. The patient was instructed to stop the treatment, but 10 months later, there was no improvement in the hyperpigmentation. This is the first report of pigmented contact dermatitis as a side-effect of topical minoxidil.
Cited in this study
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41 citations
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March 1987 in “Journal of The American Academy of Dermatology” Topical minoxidil effectively treats male pattern baldness and prevents hair loss.
44 citations
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March 1987 in “Journal of The American Academy of Dermatology” Using minoxidil on balding scalps can stimulate hair regrowth and increase blood flow. It's an effective treatment for early hair loss.
2 citations
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January 2010 in “Side effects of drugs annual” Dermatological drugs and cosmetics can cause serious side effects like cancer, allergies, and heart issues.
17 citations
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April 2002 in “Contact Dermatitis” Minoxidil 5% caused skin discoloration in a man using it for hair loss.
17 citations
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May 1998 in “Contact Dermatitis” Minoxidil can cause pustular allergic reactions on skin.
14 citations
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July 1987 in “Contact Dermatitis” Minoxidil can cause allergic skin reactions in some users.
29 citations
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August 1985 in “Contact Dermatitis” Minoxidil can cause allergic reactions like burning, itching, and red bumps.
