Status of Research on the Development and Regeneration of Hair Follicles

January 2024 in “ International Journal of Medical Sciences ”

Dan Liú, Qiaobing Xu, Xiangyuan Meng, Xiaomei Liu, Jinyu Liu

TLDR New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

The review "Status of research on the development and regeneration of hair follicles" discusses the causes of hair loss, current treatments, and potential new therapies. Hair loss, or alopecia, is a common condition that can cause significant psychological distress. The most common type is androgenetic alopecia. Current treatments, such as minoxidil, finasteride, and hair transplantation, have limitations. Emerging therapies include low-level laser therapy, micro needling, fractional radio frequency, platelet-rich plasma, and stem cell therapy. The review also discusses the role of various types of stem cells in hair follicle regeneration and hair growth. Human Dermal Papilla Cells (hDPCs) and Dermal Sheath Cells (DSCs) are essential for new hair development and renewal. Mesenchymal Stem Cells (MSCs), derived from various sources like hair follicles, umbilical cord, adipose tissue, bone marrow, and induced pluripotent stem cells, have shown potential in enhancing hair regrowth and tissue repair. The document concludes that regenerative medicine-based therapies show promise for hair loss management, but more clinical cases are needed for validation.

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4 / 4 results

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