TLDR The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.
The document reviews the complex mechanisms of hair growth and loss, and discusses current and emerging treatments for hair disorders, particularly androgenetic alopecia (AGA). The human scalp typically has 100,000 hair follicles, with hair length determined by the duration of the anagen (growth) phase. Treatments aim to promote this phase, delay the catagen (regression) phase, and prevent or reverse miniaturisation in AGA. Widely recognized treatments include finasteride and minoxidil, with finasteride inhibiting the conversion of testosterone to dihydrotestosterone (DHT) and effectively increasing hair count. Other therapies include microneedling, low-level laser light, platelet-rich plasma, fractional lasers, cellular therapy, Wnt activators, and SFRP1 antagonism. A study of 26 patients showed significant increases in hair density and count with platelet-rich plasma (PRP) injections, and a meta-analysis of 10 studies (165 participants) found PRP beneficial in AGA. The document concludes that combination therapy may provide the best long-lasting results in AGA treatment.View this study on facultyopinions.com →
Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.
Topical cetirizine 1% promotes hair growth in male androgenetic alopecia patients.
Topical finasteride helps regrow hair and reduce hair loss in men and women.
SVF-PRP therapy effectively reverses hair loss effects.
Finasteride and minoxidil work best together for hair loss.
PRP therapy improves hair density and thickness in AGA patients, even with other treatments.
Differences in gene expression and methylation patterns found in AGA patients suggest potential targets for future treatments.
Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
PRP therapy increases hair density for androgenetic alopecia.
Finasteride use doesn't cause sexual dysfunction in men with hair loss.
Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.
PRP shows promise for hair loss treatment, with three initial monthly injections and maintenance every 3-6 months.
Low-level laser therapy significantly increases hair density in adults with hair loss, with low-frequency treatment being more effective.
Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.
Daily low-dose aspirin lowers minoxidil's effectiveness for hair loss treatment.
Minoxidil helps treat pattern hair loss in both men and women.
New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.
Microneedling can help stimulate hair growth, especially when used with other treatments, but it's not better than existing therapies.
Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
Topical cetirizine improves hair density and thickness in androgenetic alopecia, but more research is needed.
Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.
Prostanoids, like prostaglandins and thromboxane A2, can both enhance and inhibit hair growth, and understanding their effects could help treat hair disorders.
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
PRP treatment may increase hair density and reduce hair loss, but more research is needed.
SVF-enhanced adipose transplantation shows potential as a hair loss treatment.
PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.
Increasing the dosage of minoxidil can help hair regrowth in women who didn't respond to the standard treatment.
PRP treatment helps hair growth and density in androgenetic alopecia patients.
Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
New model shows muscle affects hair loss differently in men and women.
ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.
Minoxidil response testing helps treat hair loss effectively and safely.
PRP injections may improve hair thickness and density in female hair loss patients.
PRP injections improve hair thickness for baldness.
Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
Sulfotransferase in hair follicles helps predict how well minoxidil works for female hair loss.
New test predicts if hair loss treatment will work.
Valproic acid increases hair count in men with hair loss.
Laser device increases hair density, safe for treating hair loss in men and women.
Low-level light therapy safely improves hair growth and thickness for androgenetic alopecia.
Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
Growth factors and microneedle therapy increase hair density in women with hair loss.
Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
Latanoprost 0.1% may effectively treat hair loss.
PGD2 stops hair growth and is higher in bald men with AGA.
Laser treatment increases hair density and thickness safely in women with hair loss.
Finasteride effectively increases hair growth in men with AGA, works better for those over 30, and may cause some side effects.
Laser treatment can stimulate hair growth for male pattern hair loss.
Finasteride helps hair growth but may cause sexual side effects.
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
New 5% minoxidil foam effectively promotes hair growth and is safe for use.
Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
5% minoxidil works better for hair growth and density, with minor irritation.
Finasteride increases hair weight and count in men with hair loss.
Finasteride 1 mg/day for five years effectively improves hair growth and slows hair loss in men with male pattern baldness, and is safe for long-term use.
Finasteride effectively treats frontal hair loss with few side effects.
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
Minoxidil helps hair growth by activating enzymes in hair follicles.
The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.
Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.
Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.