Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs
May 2023
in “Clinical, Cosmetic and Investigational Dermatology”
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research A randomized, double-blind, vehicle-controlled clinical study of hair regeneration using adipose-derived stem cell constituent extract in androgenetic alopecia
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research A randomized blinded retrospective study: the combined use of micro-needling technique, low-level laser therapy and autologous non-activated platelet-rich plasma improves hair re-growth in patients with androgenic alopecia
Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.
research Examining the Safety and Efficacy of Low-Level Laser Therapy for Male and Female Pattern Hair Loss: A Review of the Literature
Low-level laser therapy safely and effectively improves hair growth and coverage for male and female pattern hair loss.
research The effectiveness of combination therapies for androgenetic alopecia: A systematic review and meta‐analysis
Combination therapies work better than single treatments for hair loss.
research Dermoscopic assessment of microneedling alone versus microneedling with platelet-rich plasma in cases of male pattern alopecia: A split-head comparative study
research Spironolactone for treatment of female pattern hair loss
Spironolactone effectively treats female pattern hair loss with few side effects.
research Topical finasteride for the treatment of male androgenetic alopecia and female pattern hair loss: a review of the current literature
Topical finasteride helps regrow hair and reduce hair loss in men and women.
research Topical Finasteride versus Topical Spironolactone in the Treatment of Androgenetic Alopecia
research The effect of intradermal botulinum toxin on androgenetic alopecia and its possible mechanism
Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.
research Preliminary results of the use of scalp microneedling in different types of alopecia
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research Minoxidil 1 mg oral versus minoxidil 5% topical solution for the treatment of female-pattern hair loss: A randomized clinical trial
Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
research Platelet‐rich plasma and microneedling improves hair growth in patients ofandrogenetic alopecia when used as an adjuvant to minoxidil
Combining platelet-rich plasma, microneedling, and minoxidil improves hair growth.
research Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia
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research Physiopathology and current treatments of androgenetic alopecia: Going beyond androgens and anti‐androgens
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research Effectiveness and safety of low-dose oral minoxidil in male androgenetic alopecia
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research Low-level laser therapy for the treatment of androgenetic alopecia in Thai men and women: a 24-week, randomized, double-blind, sham device-controlled trial
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research Androgenetic alopecia and microneedling: Every needling is not microneedling
Microneedling improves hair growth in androgenetic alopecia when combined with minoxidil.
research The efficacy and use of finasteride in women: a systematic review
Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
research A small dose of botulinum toxin A is effective for treating androgenetic alopecia in Chinese patients
Small Botox dose effectively treats hair loss in Chinese men.
research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development
Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
research A study to compare the efficacy of platelet-rich plasma and minoxidil therapy for the treatment of androgenetic alopecia
research Controversies in the treatment of androgenetic alopecia: The history of finasteride
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research Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system
Finasteride effectively treats hair loss in Korean men for at least 5 years, with V type responding better.
research Comparative effectiveness of low-level laser therapy for adult androgenic alopecia: a system review and meta-analysis of randomized controlled trials
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research Original article: Platelet-rich plasma with microneedling in androgenetic alopecia along with dermoscopic pre- and post-treatment evaluation
PRP with microneedling effectively treats hair loss, and dermoscopy helps evaluate results.
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research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men – short version
Use minoxidil for hair loss treatment; assess results after 6 months.
research Platelet-rich plasma for androgenetic alopecia: Does it work? Evidence from meta analysis
PRP treatment may increase hair density and reduce hair loss, but more research is needed.
research Conventional and novel stem cell based therapies for androgenic alopecia
Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
research The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis
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research Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy)
Low-level laser therapy effectively treats female hair loss, increasing hair count by 51%.
research Low level light-minoxidil 5% combination versus either therapeutic modality alone in management of female patterned hair loss: A randomized controlled study
Combining low-level light therapy and minoxidil 5% is more effective for female hair loss than using either treatment alone.
research Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study
Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.
research Androgenetic alopecia: a review
Male pattern baldness involves genetics, hormones, and needs better treatments.
research A comparative study of microneedling with platelet-rich plasma plus topical minoxidil (5%) and topical minoxidil (5%) alone in androgenetic alopecia
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research Low-level laser therapy as a treatment for androgenetic alopecia
Low-level laser therapy may improve hair regrowth and thickness for androgenetic alopecia, but more research is needed.
research A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia
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research Long-term safety and efficacy of dutasteride in the treatment of male patients with androgenetic alopecia
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research Androgenetic Alopecia: An Update of Treatment Options
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research Adverse Effects and Safety of 5-alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review.
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Spironolactone may effectively treat female hair loss, especially with hyperandrogenism signs.
research Systematic review of the use of platelet-rich plasma in aesthetic dermatology
research Efficacy of platelet-rich plasma in treatment of androgenic alopecia
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research Five-year efficacy of finasteride in 801 Japanese men with androgenetic alopecia
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research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
research Response to microneedling treatment in men with androgenetic alopecia who failed to respond to conventional therapy
Microneedling can effectively promote new hair growth in men with hair loss who didn't improve with traditional treatments.
research Clinical utility and validity of minoxidil response testing in androgenetic alopecia
Minoxidil response testing helps treat hair loss effectively and safely.
research Topical minoxidil fortified with finasteride: An account of maintenance of hair density after replacing oral finasteride
Minoxidil and finasteride combo maintains hair density effectively.
research Effect of dutasteride 0.5 mg/d in men with androgenetic alopecia recalcitrant to finasteride
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research A novel finasteride 0.25% topical solution for androgenetic alopecia: pharmacokinetics and effects on plasma androgen levels in healthy male volunteers
New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
research Study of platelet-rich plasma injections in the treatment of androgenetic alopecia through an one-year period
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Sulfotransferase in hair follicles helps predict how well minoxidil works for female hair loss.
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New test predicts if hair loss treatment will work.
research Use of low-level laser therapy as monotherapy or concomitant therapy for male and female Androgenetic alopecia
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research A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia
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research Androgenetic alopecia: An update
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research A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: A pilot study
research Effects of topical application of growth factors followed by microneedle therapy in women with female pattern hair loss: A pilot study
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research Hair follicle stem cell differentiation is inhibited through cross‐talk between Wnt/β‐catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia
Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men
Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
research Finasteride, 1 mg daily administration on male androgenetic alopecia in different age groups: 10-year follow-up
Finasteride effectively increases hair growth in men with AGA, works better for those over 30, and may cause some side effects.
research Minoxidil activates β-catenin pathway in human dermal papilla cells: A possible explanation for its anagen prolongation effect
Minoxidil helps hair growth by activating the β-catenin pathway.
research Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia
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research Innovative use of spironolactone as an antiandrogen in the treatment of female pattern hair loss.
Spironolactone helps regrow hair in women with hair loss.
research Male androgenetic alopecia
Hair loss in men treated best with early medication or transplant, new treatments researched.
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