Dermoscopic Assessment of Microneedling Alone Versus Microneedling with Platelet-Rich Plasma in Cases of Male Pattern Alopecia: A Split-Head Comparative Study

    Kartikay Aggarwal, Sanjeev Gupta, Ravi Shankar Jangra, Aneet Mahendra, Anuradha Yadav, Aastha Sharma
    TLDR Microneedling alone is as effective as microneedling with platelet-rich plasma for male pattern baldness.
    The study compared microneedling (MN) alone versus microneedling with platelet-rich plasma (PRP) in treating male pattern alopecia in 30 male patients using a split-head design. Both treatments significantly increased hair thickness and density, with MN alone showing a greater increase in thickness and MN + PRP showing a greater increase in density. However, the differences were not statistically significant. Both treatments were effective, safe, and well-tolerated, but PRP did not provide additional benefits over MN alone. The study was limited by its small sample size and lack of long-term follow-up.
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