Phytochemicals as emerging therapeutic agents for alopecia treatment
January 2020
in “Elsevier eBooks”
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research Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms
research Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
research An Overview of the Biology of Platelet-Rich Plasma and Microneedling as Potential Treatments for Alopecia Areata
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research Hair Regenerative Mechanisms of Red Ginseng Oil and Its Major Components in the Testosterone-Induced Delay of Anagen Entry in C57BL/6 Mice
research Dutasteride in Androgenetic Alopecia: An Update
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research Superiority of dutasteride over finasteride in hair regrowth and reversal of miniaturization in men with androgenetic alopecia: A randomized controlled open-label, evaluator-blinded study
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research Low-level laser therapy as a treatment for androgenetic alopecia
Low-level laser therapy may improve hair regrowth and thickness for androgenetic alopecia, but more research is needed.
research Hair growth effect of traditional Chinese medicine BeauTop on androgenetic alopecia patients: A randomized double-blind placebo-controlled clinical trial
BeauTop improves hair growth in androgenetic alopecia patients.
research Perception of Hair Transplant for Androgenetic Alopecia
Hair transplants make people look more attractive, successful, approachable, and younger.
research Topical application of the Wnt/β-catenin activator methyl vanillate increases hair count and hair mass index in women with androgenetic alopecia
Methyl vanillate spray increases hair count and hair mass in women with hair loss.
research Differences in reproductive toxicology between alopecia drugs: an analysis on adverse events among female and male cases
research Long-term safety and efficacy of dutasteride in the treatment of male patients with androgenetic alopecia
Dutasteride safely promotes hair growth and reduces hair loss, with mild side effects.
research Androgenetic Alopecia: An Update of Treatment Options
Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
research Multi-therapies in androgenetic alopecia: review and clinical experiences
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research Low level laser therapy and hair regrowth: an evidence-based review
research In silico prediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss
research Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay
A new plant extract from Avicennia marina could potentially be used to treat common hair loss.
research Malva verticillataseed extracts upregulate the Wnt pathway in human dermal papilla cells
research Hair Growth: Focus on Herbal Therapeutic Agent
research The Androgenic Alopecia Protective Effects of Forsythiaside-A and the Molecular Regulation in a Mouse Model
Forsythiaside-A, a natural substance, can protect against hair loss and is more effective than current treatments, potentially making it a good option for hair loss treatment.
research Response to microneedling treatment in men with androgenetic alopecia who failed to respond to conventional therapy
Microneedling can effectively promote new hair growth in men with hair loss who didn't improve with traditional treatments.
research Drug discovery for alopecia: gone today, hair tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research The ginsenosides of Panax ginseng promote hair growth via similar mechanism of minoxidil
Ginsenosides in Panax ginseng boost hair growth like minoxidil.
research Advances in Hair Transplantation: Longitudinal Partial Follicular Unit Transplantation
research Polyphenols as novel treatment options for dermatological diseases: A systematic review of clinical trials
research Platelet-Rich Plasma for Androgenetic Alopecia
PRP injections improve hair thickness for baldness.
research Potential targets in the discovery of new hair growth promoters for androgenic alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
research The inductive effect of ginsenoside F2 on hair growth by altering the WNT signal pathway in telogen mouse skin
research A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia
Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.
research Signaling Involved in Hair Follicle Morphogenesis and Development
research Alopecia areata-successful outcome with microneedling and triamcinolone acetonide
Microneedling combined with triamcinolone can safely stimulate faster hair regrowth in people with Alopecia Areata.
research Platelet-rich plasma in androgenic alopecia: Myth or an effective tool
Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.
research Regenerative medicine and hair loss: how hair follicle culture has advanced our understanding of treatment options for androgenetic alopecia
Hair follicle culture helps develop new treatments for hair loss.
research A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata
Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.
research Hair growth-promoting activity of hot water extract of Thuja orientalis
research A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: A pilot study
research Hair growth-promoting effect of Aconiti Ciliare Tuber extract mediated by the activation of Wnt/β-catenin signaling
research Minoxidil Use in Dermatology, Side Effects and Recent Patents
Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
research Promotion of Hair Growth byRosmarinus officinalisLeaf Extract
research 5α-reductase inhibition and hair growth promotion of some Thai plants traditionally used for hair treatment
research Minoxidil activates β-catenin pathway in human dermal papilla cells: A possible explanation for its anagen prolongation effect
Minoxidil helps hair growth by activating the β-catenin pathway.
research Topical application of Polygonum multiflorum extract induces hair growth of resting hair follicles through upregulating Shh and β-catenin expression in C57BL/6 mice
research Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia
Finasteride helps hair growth but may cause sexual side effects.
research Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: A randomized, double-blind, placebo-controlled, phase III study
Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.
research Hair growth and rejuvenation: An overview
research Effect ofCuscuta reflexaRoxb on androgen-induced alopecia
research Human hair follicles contain two forms of ATP‐ sensitive potassium channels, only one of which is sensitive to minoxidil
One minoxidil-sensitive potassium channel exists in human hair follicles.
research Dutasteride improves male pattern hair loss in a randomized study in identical twins
Dutasteride helps slow hair loss and boosts hair growth.
research The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride
Dutasteride more effective for hair growth, but has more side effects than finasteride.
research The hair growth promoting effect of extract and its molecular regulation
research Androgenetic alopecia: pathogenesis and potential for therapy
Hair loss needs more research for better treatments.
research Treatments for Androgenetic Alopecia and Alopecia Areata
Minoxidil and finasteride treat hair loss; more research needed for other options.
research Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells
Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.