May 2024 in “Journal of cosmetic dermatology” This study found that early-onset male androgenetic alopecia is associated with abnormal lipid metabolism and lower levels of certain serum markers, which may serve as risk factors or protective factors for the condition.
March 2024 in “Skin research and technology” This study found that CRP levels were elevated in alopecia areata patients, with an inverse linear association between serum vitamin D and CRP levels specifically noted in ophiasis AA.
November 2023 in “Skin appendage disorders” This retrospective study conducted at two centers in west Mexico identified distinctive trichoscopic features in pediatric androgenetic alopecia, with 70% of patients being male and most showing vitamin D deficiency; topical minoxidil was effective and well-tolerated as a treatment.
July 2023 in “Dermatology practical & conceptual” In this study, hemoglobin levels were the only marker positively correlated with anagen hair ratios in patients with telogen effluvium, suggesting it may be a cost-effective initial test for management.
July 2023 in “Health science reports” In this study, researchers examined the prevalence of comorbid conditions among 402 alopecia areata patients, finding that hypothyroidism was notably more frequent in women, while hyperlipidemia was more common in men, with overall thyroid function testing suggested for these patients.
March 2023 in “Pakistan Journal of Medical and Health Sciences” This study found that premenopausal women with female-pattern hair loss had significantly lower serum vitamin D levels compared to healthy controls, suggesting a potential role of vitamin D deficiency in this condition.
March 2023 in “Photodiagnosis and Photodynamic Therapy” This study found that vitamin D levels were lower in alopecia areata patients, with trichoscopic features like broken hairs and black dots more prevalent in cases with vitamin D deficiency.
February 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that male patients with Androgenetic alopecia have higher serum leptin, lower vitamin D levels, and an altered adiponectin/leptin ratio, which may contribute to the disease's pathogenesis.
October 2022 in “Pediatric Dermatology” This study found that pediatric telogen effluvium in the US has varying triggers and management outcomes, with emotional stress and acute illness being the most common triggers.
April 2022 in “JAAD International” This study suggests that vitamin D deficiency is likely not involved in the development of frontal fibrosing alopecia, as patients showed similar vitamin D levels to those with female pattern hair loss.
In this study, higher Fitzpatrick skin type, non-summer season, and non-White race were associated with vitamin D insufficiency in US children with alopecia areata.
3 citations
,
February 2022 in “Journal of the American Academy of Dermatology” This article highlights a lack of published data on vitamin D deficiency prevalence among individuals with central centrifugal cicatricial alopecia, despite its known link to other forms of hair loss.
4 citations
,
January 2022 in “Drug design, development and therapy” This study demonstrated that intramuscular corticosteroids were effective for severe alopecia areata, with significant hair regrowth in 80.2% of patients, though a high relapse rate was noted post-treatment. Nail involvement and disease duration over six months negatively impacted outcomes.
4 citations
,
December 2021 in “Pharmacological Reports” This study found that metformin's metabolic benefits, such as reducing fat content and improving insulin sensitivity, were less pronounced in men with early-onset androgenic alopecia compared to those with normal hair growth, possibly due to differences in systemic inflammation and vitamin D status.
5 citations
,
September 2021 in “Journal of cosmetic dermatology” This study found that alopecia areata patients had significantly abnormal T3, T4, TPOAbs, ANA, and lower vitamin D levels compared to healthy controls.
2 citations
,
September 2021 In this study, serum 25-hydroxyvitamin D levels were similar between alopecia areata patients and healthy controls, though a non-significant trend toward higher vitamin D deficiency was observed among the patients.
14 citations
,
September 2021 in “Journal of Inflammation Research” This study suggests that female patients with alopecia areata, especially those with nail abnormalities and atopic diseases, may have higher rates of coexisting autoimmune diseases.
September 2021 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study found no significant difference in serum ferritin, zinc, and 25-hydroxy vitamin D levels between women with chronic telogen effluvium and healthy controls, although suboptimal levels were common in both groups.
10 citations
,
August 2021 in “Journal of Cosmetic Dermatology” This study retrospectively analyzed 3028 patients with telogen effluvium, finding that 6.2% had iron deficiency anemia and vitamin D deficiency was common, especially in women who were more often prescribed vitamin D therapy.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” This study found that vitamin D plays a major role in the premature onset of androgenetic alopecia.
31 citations
,
July 2021 in “ImmunoTargets and therapy” This review compiles current evidence on the molecular mechanisms, etiologies, and targeted immunotherapies for alopecia areata and reports no new experimental results, emphasizing the need for further research to manage the disease.
1 citations
,
July 2021 in “Fayoum University Medical Journal” This study found that vitamin D levels were significantly lower in men with androgenetic alopecia compared to healthy controls, while ferritin levels showed no significant difference.
1 citations
,
June 2021 in “International Journal of Dermatology” This study found that patients with alopecia areata had significantly lower serum vitamin D levels compared to controls, but these levels did not impact disease severity or pattern.
May 2021 in “Indian journal of forensic medicine and toxicology” This study found that adult female patients with chronic telogen effluvium had significantly lower serum ferritin and vitamin D levels compared to healthy controls, suggesting a potential association with hair loss.
May 2021 in “Indian journal of forensic medicine and toxicology” In this study, serum Vitamin D3 and ferritin levels were found to be significantly lower in women with androgenic alopecia compared to controls.
12 citations
,
May 2021 in “Clinical Interventions in Aging” This study found that men with androgenetic alopecia have different scalp biophysical characteristics in androgen-sensitive areas compared to non-sensitive areas and healthy controls.
3 citations
,
April 2021 in “Cureus” In this study, 62.7% of patients with alopecia areata had deficient vitamin D levels, yet there was no significant link between these levels and specific alopecia areata patterns.
20 citations
,
March 2021 in “Drug design, development and therapy” This review summarizes the pharmacology, mechanisms, and clinical efficacy of topical immunotherapy for alopecia areata but reports no new clinical results.
1 citations
,
January 2021 in “Turkish Journal of Medical Sciences” This study found that women with telogen effluvium had significantly lower levels of hemoglobin, ferritin, and vitamin B12 compared to other groups and men.
5 citations
,
September 2020 in “Journal of The American Academy of Dermatology” This study reported that low-dose oral minoxidil combined with a 5α-reductase inhibitor improved hair density in most men with female pattern hair loss after 6 months or more of treatment.
September 2020 in “Osmangazi tıp dergisi” This study found that vitamin D, vitamin B12, and iron deficiencies, along with thyroid dysfunction, may be associated with telogen effluvium.
6 citations
,
August 2020 in “Dermatology and Therapy” This study found that patients with alopecia areata had significantly lower serum vitamin D levels and higher odds of vitamin D deficiency, but no significant difference in serum calcium levels, compared to controls.
8 citations
,
June 2020 in “International Journal of Dermatology” This study found a significant correlation between vitamin D deficiency and the severity of androgenetic alopecia in males, suggesting that vitamin D may influence the condition's premature onset.
4 citations
,
April 2020 in “Journal of Cosmetic Dermatology” This study found that Chinese patients with alopecia areata, female pattern hair loss, and male androgenetic alopecia had significantly lower serum vitamin D levels than healthy individuals.
July 2019 in “Journal of The American Academy of Dermatology” This article discusses female pattern hair loss and concludes that the utility of lab markers for screening associated conditions remains unclear; no new clinical results are presented.
4 citations
,
July 2019 in “Vestnik Rossiĭskoĭ akademii meditsinskikh nauk / Rossiĭskaia akademiia meditsinskikh nauk” This study identified different non-genetic factors influencing androgenic alopecia in men with varying genetic risk, which may aid in developing more personalized treatments.
5 citations
,
April 2019 in “Journal of Nepal Health Research Council” This study found that vitamin D deficiency was significantly more common in alopecia areata patients than in healthy controls and was inversely correlated with disease severity.
2 citations
,
March 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This article provides no new data as it is a letter to the editor and lacks an abstract, focusing instead on discussing aspects of hair loss in the elderly without presenting research results.
37 citations
,
January 2019 in “BioMed Research International” This review highlights that scalp pruritus is a complex condition with various underlying causes, making it a challenge to diagnose and manage effectively. It emphasizes the need for comprehensive patient evaluation, history-taking, and personalized treatment strategies to address quality of life impacts.
7 citations
,
January 2019 in “Indian dermatology online journal” In this study, significantly lower serum vitamin D levels were observed in patients with alopecia areata compared to healthy controls, with an inverse correlation between vitamin D levels and disease severity or duration.
January 2019 in “Egyptian Journal of Dermatology and Venereology /Egyptian Journal of Dermatology and Venerology” This study found that patients with alopecia areata had significantly lower serum 25(OH)D levels, which may be associated with increased disease severity.
20 citations
,
January 2019 in “International journal of trichology” This study found that patients with alopecia areata had significantly lower Vitamin D levels compared to controls, with a negative correlation between Vitamin D levels and disease severity.
1 citations
,
December 2018 in “Indian journal of paediatric dermatology” This study found that children with alopecia areata had significantly lower serum vitamin D levels than healthy controls.
2 citations
,
December 2018 in “Қазақстанның клиникалық медицинасы” This study found that individuals with androgenic alopecia had higher levels of vitamin D compared to those with telogen effluvium and healthy controls.
September 2018 in “International Journal of Dermatology” This study found that Iranian patients with alopecia areata had significantly lower zinc and vitamin D levels than healthy controls, indicating these nutrients' potential role in disease management.
21 citations
,
September 2018 in “International journal of women’s dermatology” In this study, patients with lichen planopilaris showed higher prevalence of autoimmune disorders like Hashimoto's thyroiditis and hypothyroidism compared to those with seborrheic dermatitis.
100 citations
,
July 2018 in “Journal of The American Academy of Dermatology” This study found that alopecia areata is linked with a higher prevalence of systemic and psychiatric diseases, suggesting that physicians should monitor for these potential comorbidities.
37 citations
,
June 2018 in “Clinical and Experimental Medicine” This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.
13 citations
,
April 2018 in “Journal of The American Academy of Dermatology” This study found that 64.8% of patients with different types of alopecia had vitamin D deficiency, and those with lichen planopilaris and telogen effluvium had higher odds of severe deficiency compared to patients with alopecia areata.
48 citations
,
April 2018 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that individuals with alopecia areata had significantly lower serum vitamin D levels and a higher prevalence of vitamin D deficiency compared to people without the condition.
1 citations
,
January 2018 in “Journal of Steroids & Hormonal Science” This study observed no significant difference in vitamin D levels between children with alopecia areata and controls, but higher complete improvement in alopecia was noted among patients with vitamin D deficiency undergoing oral vitamin D treatment.
1 citations
,
January 2018 in “Turkiye Klinikleri Journal of Dermatology” This study found that patients with telogen effluvium had slightly lower vitamin D levels compared to healthy controls, but the difference was not statistically significant.
29 citations
,
December 2017 in “International Journal of Dermatology” This study found that vitamin D deficiency in patients with alopecia areata was associated with greater disease severity and longer duration, but not with disease pattern or vitamin D receptor expression.
28 citations
,
April 2017 in “Journal of cosmetic dermatology” This study found that while vitamin D deficiency is not the sole cause of alopecia areata, it may worsen the disease, suggesting supplementation could help in pediatric cases.
56 citations
,
March 2017 in “Journal of the American Academy of Dermatology” Alopecia areata patients often have eczema, thyroid issues, vitamin-D deficiency, and anemia.
39 citations
,
January 2017 in “Dermatologic Therapy” This study found that topical calcipotriol lotion resulted in hair regrowth in 59.1% of alopecia areata patients, with better response observed in those with lower serum vitamin D levels.
38 citations
,
January 2017 in “PPAR Research” This review discusses the role of PPAR-γ in the pathogenesis of primary cicatricial alopecia, including its involvement in lichen planopilaris and treatment trials using PPAR-agonists, and reports no new clinical results.
January 2017 in “Turkiye Klinikleri Journal of Dermatology” In this study, serum vitamin D levels were significantly lower in women with chronic telogen effluvium compared to controls, while ferritin levels showed no significant difference between the groups.
13 citations
,
December 2016 in “Egyptian Journal of Basic and Applied Sciences” This study found that patients with alopecia areata had significantly lower serum levels of 25-hydroxy vitamin D compared to control subjects.
15 citations
,
October 2016 in “PubMed” This study found that vitamin D, ferritin, and zinc deficiencies are prevalent among patients with telogen effluvium in the greater Pittsburgh area, suggesting these should be included in initial evaluations.
12 citations
,
January 2016 in “Journal of Clinical and Investigative Dermatology” This study examines how the Severity of Alopecia Tool score was used to assess Alopecia Areata in patients while excluding systemic conditions that might affect vitamin D levels, but reports no new clinical results.
23 citations
,
January 2016 in “International Journal of Trichology” This study found that women with female pattern hair loss had significantly lower serum Vitamin D3 levels compared to healthy controls.
3 citations
,
January 2015 in “Journal of the Egyptian Womenʼs Dermatologic Society” 105 citations
,
March 2014 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, patients with alopecia areata were found to have significantly lower serum vitamin D levels compared to those with vitiligo and healthy individuals, with lower levels correlating with increased disease severity.
11 citations
,
January 2014 in “Egyptian Journal of Dermatology and Venereology” This study found that women with female-pattern hair loss had significantly lower serum levels of 25-hydroxyvitamin D compared to healthy controls, but it does not establish causation.
40 citations
,
April 2013 in “Dermato-endocrinology” In this study, researchers observed vitamin D insufficiency in many patients with Alopecia Areata, suggesting its potential role in managing this autoimmune condition.
10 citations
,
January 2013 in “Faṣlnāmah-i bīmārīhā-yi pūst” This study found no significant association between vitamin D levels and alopecia areata in patients when gender was accounted for, but vitamin D levels were lower in patients with nail involvement.
14 citations
,
January 2013 in “Journal of the Egyptian Women's Dermatologic Society /Journal of the Egyptian Women's Dermatologic Society” 
62 citations
,
January 2013 in “Skin Pharmacology and Physiology” This study found that low serum ferritin and vitamin D2 levels are associated with hair loss in females with chronic telogen effluvium and female pattern hair loss, suggesting potential benefits of screening and supplementation.
54 citations
,
January 2012 in “Vitamins & Trace Elements” This study found significantly lower serum vitamin D concentrations in patients with alopecia areata compared to healthy controls, suggesting that vitamin D deficiency may be a risk factor for this autoimmune hair loss disease.
109 citations
,
June 2011 in “Molecular and Cellular Endocrinology” Vitamin D receptor mutations can cause alopecia by affecting hair growth genes.
185 citations
,
June 2011 in “Molecular and cellular endocrinology” This review discusses the regulation and function of vitamin D and its receptor in skin cells, highlighting their roles in processes such as proliferation inhibition, differentiation, and innate immunity, but reports no new results.
11 citations
,
January 2011 in “Turkish Journal of Medical Sciences” This study found that iron deficiency anemia is a key factor in the development of telogen effluvium, and higher 25-hydroxyvitamin D3 levels in TE patients may be linked to increased UV exposure.
150 citations
,
October 2010 in “The American Journal of Pathology” This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.
