Vitamin D Status in Patients with Frontal Fibrosing Alopecia: A Retrospective Study

    April 2022 in “ JAAD International ”
    Alexis Arasu, Nekma Meah, Samantha Eisman, Dmitri Wall, Rodney Sinclair
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    TLDR Women with frontal fibrosing alopecia have similar vitamin D levels to those with other hair loss types, suggesting vitamin D is not a key factor in this condition.
    The retrospective study conducted between March 2013 and February 2020 compared the baseline vitamin D levels in 100 women with Frontal fibrosing alopecia (FFA) to those in 100 women with female pattern hair loss. The mean 25-hydroxy vitamin D level in women with FFA was 68.9 nmol/L compared with 65.96 nmol/L in women with female pattern hair loss. Vitamin D insufficiency was observed in 20% of patients from both groups. The study concluded that there may be no additional requirement to measure vitamin D levels in patients with FFA compared to other forms of alopecia. The findings suggest that vitamin D deficiency is unlikely to be implicated in the pathogenesis of FFA. The study's limitations include its retrospective nature, small size, and the overrepresentation of women.
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