Risk Factors and Lipid Metabolism Characteristics of Early-Onset Male Androgenetic Alopecia: A Pilot Study

    May 2024 in “ Journal of cosmetic dermatology ”
    Shuqin Wang, Shuyun Xu, Sui Wang, Wenhao Fang, Wanrong Shi
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    TLDR Low HDL-C, uric acid, and 25-hydroxyvitamin D are risk factors for early-onset male hair loss.
    This pilot study compared 40 patients with early-onset male androgenetic alopecia (MAA) to 45 healthy controls, finding that MAA patients had significantly lower levels of HDL-C, uric acid, and 25-hydroxyvitamin D, and a higher prevalence of metabolic syndrome (37.5% vs. 17.78%). Abnormal lipid metabolism was noted, with decreased ceramides and sphingomyelins, and Cer(d38:5) and TG(15:0/18:1/18:1) identified as potential biomarkers. No significant differences were found in total testosterone levels. The study suggests lipid metabolism alterations and low HDL-C and 25(OH)D levels may be linked to early-onset MAA, highlighting the need for further research.
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      community My Theory Of Androgenic Alopecia

      in Research/Science  19 upvotes 3 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community We are manipulating our hormones, surely it's prudent to track bloodwork ?

      in Finasteride/Dutasteride  64 upvotes 1 year ago
      The conversation discusses whether individuals using hair loss treatments like Dutasteride (Dut) or Finasteride (Fin) should regularly check their hormone levels through bloodwork. Some argue it's important to monitor the effects of these medications on hormone levels, while others believe it's unnecessary if there are no side effects, citing cost and practicality concerns.

      community Blood work, is it worth to pay for it?

      in Treatment  6 upvotes 4 months ago
      The user is considering getting blood work to investigate the cause of ongoing hair loss despite using finasteride and dutasteride. Others suggest that while blood tests can provide useful health information, they may not change the hair treatment outcome.

      community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

      in Female  42 upvotes 4 years ago
      User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

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