Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review

    December 2021 in “ Cureus
    Zainab Zubair, Ketan Kantamaneni, Krishi Jalla, Mahvish Renzu, Rahul Jena, Ruchi Jain, S. Muralidharan, Vijaya Lakshmi Yanamala, Michael Alfonso
    TLDR Low vitamin D levels are linked to hair loss, and vitamin D might help treat it.
    This review highlights a significant correlation between low serum vitamin D levels and androgenetic alopecia (AGA). It includes 12 studies, such as one by Jun Zhao et al. with 777 participants, showing a strong association between low vitamin D and male AGA (P=0.0005). Another study found 82% of AGA patients were vitamin D deficient. The review suggests vitamin D deficiency may contribute to AGA and that vitamin D supplementation, especially topical analogs like calcipotriol, could promote hair growth. However, oral vitamin D can cause hypercalcemia, and further research is needed to confirm the efficacy and safety of vitamin D treatments for AGA. The review concludes that serum vitamin D levels could be a valuable diagnostic and therapeutic parameter for AGA.
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