Serum 25 Hydroxyvitamin D in Non-Scarring Alopecia: A Systematic Review and Meta-Analysis

November 2023 in “ Journal of Cosmetic Dermatology ”

Y. Chen, Xin Dong, Yi‐Xin Wang, Yu Liu, Li Xiong, Li Li

serum 25 hydroxyvitamin D non-scarring alopecia Alopecia Areata Female Pattern Hair Loss Androgenetic Alopecia Telogen Effluvium vitamin D deficiency 25(OH)D AA FPHL AGA TE

TLDR People with non-scarring hair loss often have lower vitamin D levels than those without hair loss.

The systematic review and meta-analysis of 23 studies with 10,670 participants investigated the relationship between serum 25 hydroxyvitamin D levels and non-scarring alopecia. The results showed that patients with non-scarring alopecia, including Alopecia Areata (AA), Female Pattern Hair Loss (FPHL), Androgenetic Alopecia (AGA), and Telogen Effluvium (TE), had lower levels of serum 25(OH)D and a higher incidence of vitamin D deficiency compared to controls. Factors such as age, gender, country of residence, and sample size influenced this deficiency. The study suggests that monitoring for vitamin D deficiency and providing supplements may be beneficial in managing non-scarring alopecia, but more large-scale studies are needed to confirm these findings.

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