Possible Association of Female-Pattern Hair Loss with Alteration in Serum 25-Hydroxyvitamin D Levels

This study from 9 years ago suggests a possible association between female-pattern hair loss (FPHL) and low levels of serum 25-hydroxyvitamin D (25-(OH)D). The researchers compared 60 FPHL patients with 60 healthy female controls and found that the mean serum 25-(OH)D level was significantly lower in FPHL patients. Among the FPHL patients, 78.3% had deficient levels of vitamin D. There was no significant difference in vitamin D levels between patients with and without a family history of FPHL. However, there was a significant difference in vitamin D levels among different degrees of FPHL severity. The study suggests that deficient or insufficient serum 25-(OH)D levels may play a role in the development of FPHL. The authors recommend further studies to determine if vitamin D supplementation can help control FPHL and prevent or delay its onset.