Erosive Pustular Dermatosis of the Scalp: Causes and Treatments

Erosive pustular dermatosis of the scalp (EPDS) is a rare condition that affects mainly older women and can be triggered by trauma, medications, and other conditions. Traditional treatment with high-potency topical corticosteroids often leads to recurrence and skin atrophy. Alternative treatments, including topical tacrolimus, photodynamic therapy, topical and oral dapsone, silicone gels, calcipotriol, acitretin, isotretinoin, and zinc sulfate, have shown effectiveness with fewer side effects. Cyclosporine is also effective but may have limiting adverse effects. The document highlights the importance of dermatologists recognizing the potential causes of EPDS and considering a range of treatments to reduce misdiagnosis, recurrence, and adverse effects.