TLDR Erosive pustular dermatosis is a rare skin disease that's hard to treat and affects the scalp or legs.
Erosive pustular dermatosis (EPD) of the scalp and extremities was characterized by chronic, relapsing pustules, erosions, and crusts primarily affecting older adults, often leading to significant scarring and atrophy. The condition was frequently misdiagnosed due to its resemblance to other dermatological conditions. Effective management included topical corticosteroids and calcineurin inhibitors, with some cases requiring systemic treatments. Early and accurate diagnosis was crucial to prevent long-term damage and improve patient outcomes. EPD was a rare, noninfectious inflammatory disorder that often led to secondary cicatricial alopecia, with treatment being difficult and complete resolution rare. Surgery showed success in some cases, particularly in elderly males with scalp EPD. The exact pathogenesis remained unclear, necessitating further research for better treatment strategies.
3 citations,
July 2018 in “Elsevier eBooks” Erosive pustular dermatosis of the scalp is a rare condition that causes scarring hair loss, mainly in older women, and requires ongoing treatment.
13 citations,
January 2012 in “Case reports in dermatological medicine” An 84-year-old man got a rare scalp condition from using imiquimod cream, which was cured with systemic steroids.
36 citations,
January 2012 in “Dermatology” Stopping gefitinib improved scalp condition in a woman with lung cancer.
22 citations,
August 2011 in “Journal of the American Academy of Dermatology” Topical tacrolimus can effectively treat erosive pustular dermatosis and related hair loss.
52 citations,
February 2009 in “Journal of the American Academy of Dermatology” A 93-year-old woman developed a rare scalp condition after therapy, which improved with steroids, not antibiotics.
23 citations,
November 2007 in “Journal of cutaneous medicine and surgery” Topical tacrolimus effectively treated scalp lesions, reversed skin atrophy, and promoted hair growth.
187 citations,
May 1979 in “British Journal of Dermatology” Topical steroids can manage chronic scalp pustules in elderly women.
98 citations,
May 2008 in “British Journal of Dermatology” There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
18 citations,
January 2020 in “Journal of the European Academy of Dermatology and Venereology” High-potency steroids or tacrolimus are effective treatments for Erosive Pustular Dermatosis of the Scalp.
1 citations,
December 2022 in “Life” Topical corticosteroids are the main treatment for Erosive Pustular Dermatosis, but recurrence is common after stopping treatment.
13 citations,
September 2019 in “Clinical, Cosmetic and Investigational Dermatology” Early treatment of EPDS can improve outcomes and reduce recurrence risk.
3 citations,
July 2018 in “Elsevier eBooks” Erosive pustular dermatosis of the scalp is a rare condition that causes scarring hair loss, mainly in older women, and requires ongoing treatment.
