Erosive Pustular Dermatosis of the Scalp: A Multicenter Study

    Michela Starace, Matilde Iorizzo, Ralph M. Trüeb, Vincenzo Piccolo, Giuseppe Argenziano, Francisco Gómez Camacho, Yu. A. Gallyamova, Lidia Rudnicka, Ignacio J. Umbert, Anna Lyakhovitsky, Sergio Vañó‐Galván, Andy Goren, Aurora Alessandrini, Francesca Bruni, Bianca Maria Piraccini
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    TLDR High-potency steroids or tacrolimus are effective treatments for Erosive Pustular Dermatosis of the Scalp.
    The multicentre retrospective study included 56 patients with Erosive Pustular Dermatosis of the Scalp (EPDS), a condition that leads to scarring alopecia. The study aimed to understand the epidemiology, clinical findings, and treatment of EPDS. It found that local trauma was a common history in 60% of cases, suggesting its role in the condition's pathogenesis. Trichoscopy and histopathology were important diagnostic tools, revealing characteristic features of EPDS. The study concluded that high-potency steroids or tacrolimus are effective first-line treatments, with topical steroids showing a 50% reduction in inflammatory signs and topical tacrolimus effective in all treated patients. Other treatments such as systemic steroids, dapsone, and wound dressings were also mentioned, with the importance of clinical suspicion and familiarity with EPDS highlighted for accurate diagnosis and management.
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