Possible Association of Female-Pattern Hair Loss with Alteration in Serum 25-Hydroxyvitamin D Levels

The study investigated the association between female-pattern hair loss (FPHL) and serum 25-hydroxyvitamin D levels in 72 female patients compared to 72 healthy controls. Results showed that FPHL patients had significantly lower vitamin D levels (15.4 ± 8.25 ng/ml) than controls (46.42 ± 19.92 ng/ml). The severity of hair loss, classified using Ludwig's scale, also correlated with vitamin D levels, with the most severe cases having higher levels. The study concluded that vitamin D deficiency is linked to higher rates of hair loss in premenopausal women, particularly in the 26-30 age group, suggesting that serum 25-(OH) D levels may play a role in FPHL etiology.