The Value of Genetic and Non-Genetic Factors in the Emergence and Development of Androgenetic Alopecia in Men: Multifactor Analysis

July 2019 in “ Vestnik Rossiĭskoĭ akademii meditsinskikh nauk / Rossiĭskaia akademiia meditsinskikh nauk ”

Irina N Kondrakhina, Картушина Елена Никифоровна, Dmitry A. Verbenko, Васин Владимир Анатольевич, A M Zatevalov, Захаров Кирилл Михайлович, Alexey A. Kubanov, Кряжков Владимир Алексеевич, Dmitry Deryabin, Дмитриенко Алексей Геннадиевич

androgenetic alopecia genetic predisposition non-genetic factors lifestyle diet environmental influences personalized treatment strategies AGA

TLDR Both genetics and lifestyle factors contribute to male pattern baldness.

The study analyzed the roles of genetic and non-genetic factors in the development of androgenetic alopecia (AGA) in men, involving 500 participants. It found that genetic predisposition significantly influenced AGA, but non-genetic factors such as lifestyle, diet, and environmental influences also contributed to its onset and progression. The research highlighted the multifactorial nature of AGA, emphasizing the need for a combined approach in understanding and predicting the condition. The findings suggested that personalized treatment strategies should consider both hereditary and external factors.

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Research cited in this study

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Male pattern baldness involves genetics, hormones, and needs better treatments.

research Changes of Serum Trace Elements Level in Patients with Alopecia Areata: A Meta-Analysis

23 citations, February 2017 in “Journal of dermatology”

Low serum levels of zinc and selenium may increase the risk of alopecia areata.

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7 citations, January 2017 in “Journal of cosmetology & trichology”

Good nutrition is crucial for healthy hair and can help with hair loss without medication.

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20 citations, May 2016 in “Journal of Cosmetic Dermatology”

Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.

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48 citations, May 2015 in “PLOS ONE”

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

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3 citations, May 2014 in “InTech eBooks”

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

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11 citations, January 2010 in “Springer eBooks”

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