SNP Variation in Male Pattern Hair Loss in Russians with Different Dihydrotestosterone Levels

    December 2018 in “ Meta Gene ”
    Irina N Kondrakhina, Dmitry A. Verbenko, A M Zatevalov … Dmitry Deryabin
    Studysummary This study applied a prediction model based on five SNPs to Russian males with male pattern hair loss, finding a significant association between the AR genomic region and high dihydrotestosterone levels in these patients.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 13

    1. GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk Nature Communications · 2017
    2. Meta-Analysis Identifies Novel Risk Loci and Yields Systematic Insights into the Biology of Male-Pattern Baldness Nature communications · 2017
    3. Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us? Experimental Dermatology · 2016
    4. Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population Dermatology · 2016
    5. Evaluation of DNA Variants Associated with Androgenetic Alopecia and Their Potential to Predict Male Pattern Baldness PLOS ONE · 2015
    6. Induction of Insulin-Like Growth Factor-I by Cepharanthine from Dermal Papilla Cells: A Novel Potential Pathway for Hair Growth Stimulation The Journal of Dermatology · 2013
    7. Evidence for Two Independent Functional Variants for Androgenetic Alopecia Around the Androgen Receptor Gene Experimental Dermatology · 2010
    8. Fine Mapping of the Human AR/EDA2R Locus in Androgenetic Alopecia British Journal of Dermatology · 2010
    9. Androgen Receptor Copy Number Variation and Androgenetic Alopecia: A Case-Control Study PLOS ONE · 2009
    10. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    11. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    12. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    13. Androgens and Human Hair Growth Clinical endocrinology · 1994