SNP Variation in Male Pattern Hair Loss in Russians with Different Dihydrotestosterone Levels

December 2018 in “ Meta Gene ”

Irina N Kondrakhina, Dmitry A. Verbenko, A M Zatevalov, Alexey A. Kubanov, Dmitry Deryabin

single nucleotide polymorphisms male pattern hair loss dihydrotestosterone DHT genetic association artificial neural network SNPs MPHL

Studysummary This study applied a prediction model based on five SNPs to Russian males with male pattern hair loss, finding a significant association between the AR genomic region and high dihydrotestosterone levels in these patients.

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This study investigated the association between single nucleotide polymorphisms (SNPs) and male pattern hair loss (MPHL) in Russians with different dihydrotestosterone (DHT) levels. The study found that certain SNPs were associated with an increased risk of MPHL, and that the genetic association strength was influenced by DHT levels. The study also used an artificial neural network to predict MPHL based on these SNPs. Overall, this study provides insight into the genetic factors that contribute to MPHL in Russians.

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