SNP Variation in Male Pattern Hair Loss in Russians with Different Dihydrotestosterone Levels

February 2019 in “ Meta Gene ”

Irina N Kondrakhina, Dmitry A. Verbenko, A M Zatevalov, Alexey A. Kubanov, Dmitry Deryabin

single nucleotide polymorphisms male pattern hair loss dihydrotestosterone DHT genetic association artificial neural network SNPs MPHL

TLDR Certain gene variations increase male hair loss risk, influenced by hormone levels.

This study investigated the association between single nucleotide polymorphisms (SNPs) and male pattern hair loss (MPHL) in Russians with different dihydrotestosterone (DHT) levels. The study found that certain SNPs were associated with an increased risk of MPHL, and that the genetic association strength was influenced by DHT levels. The study also used an artificial neural network to predict MPHL based on these SNPs. Overall, this study provides insight into the genetic factors that contribute to MPHL in Russians.

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