TLDR Cepharanthine may help hair growth by increasing IGF-I in scalp cells.
The study from 2013 investigated the effects of cepharanthine (CEP) on hair growth, focusing on its ability to induce insulin-like growth factor-1 (IGF-I) in dermal papilla cells (DPC) from three male patients with androgenetic alopecia (AGA). The results showed that CEP at 0.1 µg/mL significantly increased both IGF-I mRNA expression and IGF-I protein secretion in DPC cultures. These findings suggest that CEP could stimulate hair growth by enhancing IGF-I production, presenting a potential new treatment for AGA and other hair loss conditions. The authors propose that topical application of CEP may be an effective method for combating hair loss.
23 citations,
September 2011 in “Journal of Dermatological Science” Red LED light helps mouse hair grow by increasing growth factors from skin cells.
49 citations,
August 2003 in “Journal of The American Academy of Dermatology” Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
173 citations,
July 1995 in “Biochemical and biophysical research communications” Male hormones promote hair cell growth by using a growth factor from nearby skin cells.
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.
1 citations,
January 2016 in “Hair therapy & transplantation” Liposomal cepharanthine lotion speeds up hair growth in men with early balding.
3 citations,
March 2016 in “Journal of Cosmetic Dermatology” GPIGS peptide increases thick hair growth in balding Japanese men.
34 citations,
May 2012 in “International Journal of Molecular Sciences” Dieckol from Ecklonia cava may help hair growth and could be a potential hair loss treatment.
30 citations,
September 2004 in “Experimental Dermatology” Scalp hair follicle culture has limits for testing minoxidil's hair growth effects.
