Chronic Telogen Effluvium in Women: Role of Micronutrients, a Case-Control Study in Northern Iran

    Narges Alizadeh, Rana Rafiei, Abbas Darjani, Hojat Eftekhari, Kaveh Gharaei Nejad, Elahe Rafiei, Maryam Sadegh Vishkaei
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    TLDR The study concluded that low iron and vitamin D levels in women might play a role in chronic hair loss, despite no significant difference between those with and without hair loss.
    In 2021, a case-control study was conducted on 166 premenopausal urban women, 83 with chronic telogen effluvium (CTE) and 83 without hair loss, to compare ferritin, zinc, and 25-hydroxy vitamin D (25OH vitamin D) levels. The study found no significant difference in these micronutrient levels between the two groups. However, over 50% of participants in both groups had suboptimal levels of ferritin (<40 μg/l), and about one-third had 25OH vitamin D deficiency. Despite the lack of significant difference, the study concluded that the role of these micronutrients in CTE could not be dismissed, suggesting that common suboptimal levels of ferritin and 25OH vitamin D in women may have contributed to the nonsignificant difference.
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