10 citations
,
April 2020 in “Dermatology and therapy” In this study of 35 patients with scalp alopecia areata, calcipotriol ointment led to faster and greater hair regrowth than clobetasol, though differences were not statistically significant.
19 citations
,
July 2019 in “Journal of Cosmetic Dermatology” This study found that in patients with patchy alopecia areata, certain trichoscopic features like upright regrowing hairs and pigtail hairs are positive predictive markers for treatment success.
5 citations
,
April 2019 in “Journal of Nepal Health Research Council” This study found that vitamin D deficiency was significantly more common in alopecia areata patients than in healthy controls and was inversely correlated with disease severity.
20 citations
,
January 2019 in “International journal of trichology” This study found that patients with alopecia areata had significantly lower Vitamin D levels compared to controls, with a negative correlation between Vitamin D levels and disease severity.
37 citations
,
June 2018 in “Clinical and Experimental Medicine” This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.
191 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
29 citations
,
December 2017 in “International Journal of Dermatology” This study found that vitamin D deficiency in patients with alopecia areata was associated with greater disease severity and longer duration, but not with disease pattern or vitamin D receptor expression.
290 citations
,
December 2017 in “Journal of The American Academy of Dermatology” This article reviews the epidemiology, clinical evaluation, and pathogenesis of alopecia areata and highlights recent advancements, but it does not report new clinical findings.
28 citations
,
April 2017 in “Journal of cosmetic dermatology” This study found that while vitamin D deficiency is not the sole cause of alopecia areata, it may worsen the disease, suggesting supplementation could help in pediatric cases.
74 citations
,
May 2016 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” This review identifies shared interferon gamma-driven immune pathways in vitiligo and alopecia areata, revealing potential targets for new treatments, but reports no clinical results.
32 citations
,
March 2015 in “The Journal of Clinical Endocrinology & Metabolism” In this study, alopecia areata was associated with thyroid autoimmunity but not islet autoimmunity, correlating with specific class II HLA haplotypes linked to various autoimmune diseases.
105 citations
,
March 2014 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, patients with alopecia areata were found to have significantly lower serum vitamin D levels compared to those with vitiligo and healthy individuals, with lower levels correlating with increased disease severity.
109 citations
,
June 2011 in “Molecular and Cellular Endocrinology” Vitamin D receptor mutations can cause alopecia by affecting hair growth genes.
391 citations
,
January 2010 in “Journal of The American Academy of Dermatology” This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.
