Vitamin D Deficiency in Non-Scarring and Scarring Alopecias: A Systematic Review and Meta-Analysis

    October 2024 in “ Frontiers in Nutrition
    Tanat Yongpisarn, Kasama Tejapira, Kunlawat Thadanipon, Poonkiat Suchonwanit
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    TLDR Vitamin D deficiency is common in people with certain types of hair loss, like alopecia areata and female pattern hair loss.
    This systematic review and meta-analysis examined the link between vitamin D deficiency (VDD) and various alopecia types, including alopecia areata (AA), androgenetic alopecia (AGA), telogen effluvium (TE), and primary cicatricial alopecia (PCA), across 81 studies with 15,339 patients. The findings indicate a significant association between VDD and alopecia, with different prevalence and severity levels among the types. The study suggests vitamin D's role in hair follicle cycling and immune modulation, potentially contributing to alopecia pathogenesis. However, the causality and consistency of these associations are still debated, necessitating further research to clarify vitamin D's role in alopecia.
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