Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles

    Xiangyu Lin, Zhu Liang, Jing He
    Studysummary This review covers the structure, development, cycle, and molecular regulation of hair follicles but does not report new results, aiming to offer insights for addressing hair follicle-related diseases.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 58

    1. Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition from Telogen to Anagen Phase Frontiers in Cell and Developmental Biology · 2022
    2. Exosomal miRNA-181a-5p from Hair Follicle Dermal Papilla Cells Promotes Hair Follicle Growth and Development via the Wnt/β-Catenin Signaling Pathway International journal of biological macromolecules · 2022
    3. Comprehensive Analysis of LncRNA AC010789.1 Delays Androgenic Alopecia Progression by Targeting MicroRNA-21 and the Wnt/β-Catenin Signaling Pathway in Hair Follicle Stem Cells Frontiers in Genetics · 2022
    4. Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation Biomedicines · 2022
    5. Hair Growth-Promoting Effect of Resveratrol in Mice, Human Hair Follicles, and Dermal Papilla Cells Clinical, Cosmetic and Investigational Dermatology · 2021
    6. Niacinamide Down-Regulates the Expression of DKK-1 and Protects Cells from Oxidative Stress in Cultured Human Dermal Papilla Cells Clinical, Cosmetic and Investigational Dermatology · 2021
    7. Comprehensive Transcriptome and Methylome Analysis Delineates the Biological Basis of Hair Follicle Development and Wool-Related Traits in Merino Sheep BMC Biology · 2021
    8. Recent Progress in Understanding the Effect of Sympathetic Nerves on Hair Follicle Growth Frontiers in Cell and Developmental Biology · 2021
    9. MiR-22 Promotes Stem Cell Traits Via Activating Wnt/β-Catenin Signaling In Cutaneous Squamous Cell Carcinoma Oncogene · 2021
    10. Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-Catenin in Inner Mongolia Cashmere Goats Frontiers in genetics · 2021
    11. Liposomal Honokiol Promotes Hair Growth Via Activating Wnt3a/β-Catenin Signaling Pathway and Downregulating TGF-β1 in C57BL/6N Mice Biomedicine & Pharmacotherapy · 2021
    12. Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway Frontiers in Cell and Developmental Biology · 2021
    13. Micro-Current Stimulation Has Potential Effects of Hair Growth Promotion on Human Hair Follicle-Derived Papilla Cells and Animal Model International Journal of Molecular Sciences · 2021
    14. Nanoscale Microenvironment Engineering for Expanding Human Hair Follicle Stem Cells and Revealing Their Plasticity Journal of Nanobiotechnology · 2021
    15. Stem and Progenitor Cells in Sebaceous Gland Development, Homeostasis, and Pathologies Experimental dermatology · 2021
    16. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    17. Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation Journal of Investigative Dermatology · 2021
    18. Stem Cells from Human Exfoliated Deciduous Teeth Promote Hair Regeneration in Mice Cell Transplantation · 2021
    19. Hair Growth Promoting Effects of 650 nm Red Light Stimulation on Human Hair Follicles and Study of Its Mechanisms via RNA Sequencing Transcriptome Analysis Annals of Dermatology · 2021
    20. Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation Frontiers in Cell and Developmental Biology · 2020
    21. Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells In Vitro by Forming a Complex With Tcf4 and β-Catenin Frontiers in Cell and Developmental Biology · 2020
    22. All-Trans-Retinoic Acid Inhibits Mink Hair Follicle Growth by Inhibiting Proliferation and Inducing Apoptosis of Dermal Papilla Cells Through TGF-β2/Smad2/3 Pathway Acta histochemica · 2020
    23. LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells Frontiers in Genetics · 2020
    24. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020
    25. EZH2-Mediated Inhibition of MicroRNA-22 Promotes Differentiation of Hair Follicle Stem Cells by Elevating STK40 Expression Aging · 2020
    26. Human Hair Outer Root Sheath Cells and Platelet-Lysis Exosomes Promote Hair Inductivity of Dermal Papilla Cells Tissue Engineering and Regenerative Medicine · 2020
    27. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
    28. Dicer- and Bulge Stem Cell-Dependent MicroRNAs During Induced Anagen Hair Follicle Development Frontiers in cell and developmental biology · 2020
    29. Deficiency of Crif1 in Hair Follicle Stem Cells Retards Hair Growth Cycle in Adult Mice PloS one · 2020
    30. 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes Frontiers in cell and developmental biology · 2020
    31. Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture Frontiers in Pharmacology · 2020
    32. Isolating Dermal Papilla Cells from Human Hair Follicles Using Microdissection and Enzyme Digestion Methods in molecular biology · 2020
    33. Protective Effects of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Against Dexamethasone-Induced Apoptotic Cell Death in Hair Follicles International Journal of Molecular Medicine · 2019
    34. Hes1 Regulates Anagen Initiation and Hair Follicle Regeneration Through Modulation of Hedgehog Signaling Stem Cells · 2019
    35. Hair Follicle Differentiation-Specific Keratin Expression in Human Basal Cell Carcinoma Clinical and Experimental Dermatology · 2019
    36. Epidermal Stem Cells in Wound Healing and Their Clinical Applications Stem Cell Research & Therapy · 2019
    37. Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation British Journal of Dermatology · 2019
    38. The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics International Journal of Molecular Sciences · 2019
    39. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    40. Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms International Journal of Molecular Sciences · 2018
    41. Hair Biology Facial Plastic Surgery Clinics of North America · 2018
    42. Baicalin Increases Hair Follicle Development by Enhancing Canonical Wnt/β-Catenin Signaling and Activating Dermal Papilla Cells in Mice International Journal of Molecular Medicine · 2018
    43. Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids Cell Reports · 2018
    44. MicroRNAs in the Skin: Role in Development, Homeostasis, and Regeneration Clinical Science · 2017
    45. Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth Journal of Investigative Dermatology · 2017
    46. Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2017
    47. Regeneration of Fat Cells from Myofibroblasts During Wound Healing Science · 2017
    48. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015
    49. Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations Cell · 2015
    50. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    51. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    52. Shh Maintains Dermal Papilla Identity and Hair Morphogenesis via a Noggin–Shh Regulatory Loop Genes & Development · 2012
    53. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    54. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011
    55. Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen) ˜The œAmerican journal of pathology · 2006
    56. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    57. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    58. Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles Wound Repair and Regeneration · 1998

    Related research 6

    1. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    2. The Effects of Gamma Rays on the Regeneration of Hair Follicles Are Carried Over to Later Hair Cycles International Journal of Radiation Biology · 2015
    3. Betacellulin Regulates Hair Follicle Development and Hair Cycle Induction and Enhances Angiogenesis in Wounded Skin Journal of Investigative Dermatology · 2007
    4. Miz1 Is Required for Hair Follicle Structure and Hair Morphogenesis Journal of cell science · 2007
    5. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    6. Dermal-Epidermal Interactions in Hair Follicle Development and Cycling Clinics in dermatology · 1988