Stem Cells from Human Exfoliated Deciduous Teeth Promote Hair Regeneration in Mice

    January 2021 in “ Cell Transplantation ”
    Xiaoshuang Zhang, Lei Tong, Peng Chen … Hongwu Du
    Studysummary This study found that stem cells from human deciduous teeth promoted hair regeneration and increased hair formation in mice, suggesting a potential mechanism involving the Shh/Gli1 pathway.
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    Research cited in this study 16

    1. SIRT7 Activates Quiescent Hair Follicle Stem Cells to Ensure Hair Growth in Mice EMBO journal · 2020
    2. Retracted Article: Up-Regulated lncRNA5322 Elevates MAPK1 to Enhance Proliferation of Hair Follicle Stem Cells as a ceRNA of microRNA-19b-3p Cell cycle/Cell cycle (Georgetown, Tex. Online) · 2019
    3. Dental Derived Stem Cell Conditioned Media for Hair Growth Stimulation PLOS ONE · 2019
    4. Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms International Journal of Molecular Sciences · 2018
    5. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration Cell Stem Cell · 2018
    6. Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1-Dependent Manner Journal of Investigative Dermatology · 2018
    7. Hair Regenerative Mechanisms of Red Ginseng Oil and Its Major Components in the Testosterone-Induced Delay of Anagen Entry in C57BL/6 Mice Molecules · 2017
    8. Hairy Tale of Signaling in Hair Follicle Development and Cycling Seminars in cell & developmental biology · 2012
    9. Biology of the Hair Follicle: The Basics Seminars in Cutaneous Medicine and Surgery · 2006
    10. Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression Cancer Research · 2006
    11. Structural Optimization of Pep7, a Small Peptide Extracted from Epimorphin, for Effective Induction of Hair Follicle Anagen Experimental Dermatology · 2005
    12. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    13. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    14. Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment Journal of The American Academy of Dermatology · 2002
    15. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    16. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000

    Related research 1

    1. Activation of the Transcription Factor Gli1 and the Sonic Hedgehog Signaling Pathway in Skin Tumors Nature · 1997