Human Teeth Are Useful Even After They Are Shed: Why Discard Them?

    September 2023 in “ Dentistry
    Meghna Bhandary, Rachaita Chhabra, K. Ananya Rao, Mohammad Shahid
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    TLDR Baby teeth stem cells can potentially grow organs and treat diseases.
    The document discusses the potential of stem cells from human exfoliated deciduous teeth (SHED) in regenerative medicine, tissue engineering, and dentistry. SHED, often discarded as biological waste, can be used to grow organs, including teeth, hearts, and livers, with no risk of rejection as they are made from the patient's own cells. They have potential in treating diseases like Parkinson's, spinal cord injuries, type 1 diabetes, and more. SHED have been found to be highly proliferative and capable of differentiating into a variety of cell types. They have shown promise in various applications such as dentin pulp complex regeneration, bio root regeneration, periodontal regeneration, and more. They also have immunomodulatory properties, which can be beneficial in treating conditions involving inflammation. Despite their potential, challenges such as ethical issues, potential mutations, and difficulties in transplantation and differentiation exist. The document suggests that banking of SHED could be a reasonable option considering its potential therapeutic applications.
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