Dicer- and Bulge Stem Cell-Dependent MicroRNAs During Induced Anagen Hair Follicle Development

    May 2020 in “ Frontiers in cell and developmental biology ”
    Neda Vishlaghi, Thomas S. Lisse
    TLDR MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
    The study investigated the role of Dicer and bulge stem cell-dependent microRNAs in hair follicle development during the anagen phase. It found that Dicer, essential for microRNA processing, was crucial for the proper function and maintenance of hair follicle stem cells, with its absence leading to impaired hair growth and follicle development. Tarbp2 was not essential for anagen development. The research highlighted the importance of Dicer-dependent microRNA biogenesis in post-natal hair follicle growth and suggested that targeting microRNA pathways could be a potential therapeutic strategy for hair loss conditions. The study provided insights into the molecular mechanisms governing hair growth and the potential for developing new treatments for alopecia.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results

    Related Community Posts Join

    6 / 88 results

      community Where to find Botox online

      in Treatment  6 upvotes 4 years ago
      The user is looking for a place to buy genuine Botox online for scalp use. They are seeking recommendations for reliable sources.

      community Going for mixology with fingers crossed.

      in Treatment 3 weeks ago
      The user is experimenting with a mix of topical treatments, including finasteride and minoxidil, to improve hair growth, particularly at the temples and core. They are also trying various oils, despite skepticism about their effectiveness, to see if they can enhance results without causing harm.

      community Two months of minoxidil 5mg only!

      in Progress Pictures  197 upvotes 3 weeks ago
      The conversation discusses hair loss treatments, specifically the use of minoxidil and the potential addition of finasteride. The user has seen some progress with minoxidil but is hesitant about finasteride due to possible side effects, while others suggest combining both for better long-term results.

      community 1.5 Year Hair Restoration Journey - Stem Cells, PRP, Minoxidil, Topical Finasteride

      in Progress Pictures  26 upvotes 1 year ago
      A user shared their 1.5-year hair restoration journey, successfully using mesenchymal stem cell therapy, Platelet Rich Plasma (PRP) injections, and a topical compound of finasteride and minoxidil, avoiding a hair transplant and oral finasteride. They experienced significant hair regrowth, particularly crediting the stem cell therapy for quick initial results.

      community DUT Risk profile for having kids?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      The user has been using a hair loss treatment including oral Minoxidil, topical Minoxidil with Tretinoin and Finasteride, and is considering adding Dutasteride but is concerned about the potential side effects and risks regarding fertility. A reply suggests that having children while on these medications should be fine, advising to avoid letting the partner come into contact with the drugs.

      community Forgot min+fin whilst travelling

      in General  82 upvotes 4 weeks ago
      The user forgot their minoxidil and finasteride while traveling in Indonesia and is concerned about hair loss. They are advised that a 6-week break might cause some shedding but not drastic changes, and it's safer to wait for friends to bring the medication due to strict drug laws.

    Similar Research

    5 / 890 results