MicroRNA-148a Controls Epidermal and Hair Follicle Stem/Progenitor Cells by Modulating the Activities of ROCK1 and ELF5

    Maximilian E. Pickup, Ankit Patel, Mohammed I. Ahmed
    Studysummary This study found that miR-148a plays a significant role in regulating skin homeostasis and hair follicle cycling, influencing stem cell activity and development in mice.
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    Research cited in this study 10

    1. Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes During Skin Aging Journal of Investigative Dermatology · 2019
    2. MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2 Journal of cellular physiology · 2019
    3. ROCK Inhibitor Y-27632 Maintains the Propagation and Characteristics of Hair Follicle Stem Cells PubMed · 2018
    4. MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway Journal of Cell Biology · 2014
    5. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    6. Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin Development · 2012
    7. Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle ˜The œFASEB journal · 2010
    8. MicroRNA Control of Signal Transduction Nature Reviews Molecular Cell Biology · 2010
    9. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    10. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003

    Related research 2

    1. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018
    2. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011