Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-Catenin in Inner Mongolia Cashmere Goats

    July 2021 in “ Frontiers in genetics ”
    Junyang Liu, Qing Mu, Zhihong Liu, Yan Wang, Jiasen Liu, Zhiqiang Wu, Wendian Gong, Zeyu Lu, Fei Zhao, Yanjun Zhang, Ruijun Wang, Rui Su, Jinquan Li, Hong‐Mei Xiao, Yanhong Zhao
    TLDR Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.
    The research conducted on 12 adult female Inner Mongolia Cashmere Goats found that melatonin, a hormone that regulates sleep, significantly influences the periodic growth of cashmere. The study showed that melatonin upregulates the expression of Wnt10b and β-catenin, proteins crucial for hair growth, and promotes the development of secondary hair follicles. The melatonin-implanted goats experienced cashmere growth 2 months earlier than the control group and had a significantly higher number of secondary hair follicles. The study also found that melatonin concentration in the implanted group was approximately 10.42 times higher than in the control group. The results suggest that melatonin could potentially enhance cashmere production by regulating the expression of genes related to hair follicle development.
    Discuss this study in the Community →

    Research cited in this study

    15 / 15 results

    Related Community Posts Join

    6 / 354 results

      community Thoughts of this sub on Melatonin?

      in Research/Science  3 upvotes 9 months ago
      Melatonin, gingko biloba, and biotin are effective for treating hair loss with good tolerability. Alternatives like dutasteride, minoxidil, and other peptides are also discussed.

      community Melatonin emerging as new treatment for androgenic alopecia?

      in Update  35 upvotes 11 months ago
      Melatonin is being considered as a potential treatment for androgenic alopecia, with some users discussing its effects and combining it with other treatments like minoxidil and finasteride. Concerns about melatonin's impact on hormones and side effects from other treatments like ketoconazole were also discussed.

      community Is anyone using melatonin for hair loss?

      in Research/Science  9 upvotes 1 year ago
      Melatonin is being discussed as a potential treatment for hair loss, with questions about its effectiveness and whether it should be used topically or orally. No specific conclusions or personal experiences were shared.

      community Melatonin options for Europe??? *Retrograde Alopecia*

      in Product  3 upvotes 1 year ago
      A user is considering using melatonin for hair recovery on the side and neck area but is unsure about the best options in Europe and whether a dietary supplement form can be applied to the scalp. They found a product but are hesitant and seeking opinions on its use for alopecia.

      community Optimal dose for topical Melatonin

      in Treatment  6 upvotes 2 years ago
      The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

    Related Research

    3 / 3 results