Unraveling the Secret Life of the Hair Follicle: From Fungi to Innovative Hair Loss Therapies

The document discusses the evolution of hair research, beginning with the discovery of fungi as a cause of tinea capitis in the 19th century and the role of Malassezia in seborrhoeic dermatitis. It highlights the impact of the wool industry on hair research, including the first detailed description of the hair cycle. The paper also notes significant advancements in hair loss treatments, such as minoxidil and finasteride for androgenetic alopecia, and the recent interest in Janus kinase inhibitors for alopecia areata. Additionally, it mentions the importance of fundamental research into hair follicle biology and stem cells. The edition of Experimental Dermatology from which this editorial is taken includes a variety of articles on hair biology, disease, and therapeutics, as well as other skin appendages like eccrine sweat glands and nails. The document emphasizes the importance of considering patient perspectives in hair loss research, as indicated by a study under the UK James Lind Alliance, which suggests that patient priorities can guide future research and support grant applications.