Comprehensive Transcriptome and Methylome Analysis Delineates the Biological Basis of Hair Follicle Development and Wool-Related Traits in Merino Sheep

    September 2021 in “ BMC Biology ”
    Bingru Zhao, Hanpeng Luo, Junmin He … Kechuan Tian
    Studysummary This study found that specific gene expressions during different stages of hair follicle development in Merino sheep are linked to wool-related traits, and may also be relevant to human skin, metabolic, and immune traits.
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    Research cited in this study 16

    1. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    2. HNG, A Humanin Analogue, Promotes Hair Growth By Inhibiting Anagen-To-Catagen Transition International Journal of Molecular Sciences · 2020
    3. Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat Cells · 2020
    4. New Aspects of Vitamin D Metabolism and Action: Addressing the Skin as Source and Target Nature Reviews Endocrinology · 2020
    5. The Inconsistent Regulation of HOXC13 on Different Keratins and the Regulation Mechanism on HOXC13 in Cashmere Goat (Capra Hircus) BMC Genomics · 2018
    6. Transcriptome Reveals Long Non-Coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin Frontiers in physiology · 2018
    7. Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling Molecular therapy · 2017
    8. Epidermal Growth Factor Promotes Proliferation of Dermal Papilla Cells via Notch Signaling Pathway Biochimie · 2016
    9. The Notch Intracellular Domain Has an RBPj-Independent Role During Mouse Hair Follicular Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2016
    10. Epithelial Skin Biology: Stem Cells and Epidermal Homeostasis Current Topics in Developmental Biology · 2016
    11. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    12. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    13. Biology of the Wool Follicle: An Excursion into a Unique Tissue Interaction System Waiting to Be Rediscovered Experimental Dermatology · 2006
    14. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    15. Characterization of Hair Follicle Antigens Targeted by the Anti-Hair Follicle Immune Response Journal of Investigative Dermatology Symposium Proceedings · 2003
    16. A New Mutation Rim3 Resembling Re Den Is Mapped Close to Retinoic Acid Receptor Alpha (Rara) Gene on Mouse Chromosome 11 Mammalian Genome · 1998