Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen)
December 2006
in “
The American journal of pathology
”
Edar signaling hair follicle cycling anagen catagen apoptosis outer root sheath keratinocytes genetic ablation pharmacological inhibition TUNEL-positive cells activated caspase 3 XIAP anti-apoptotic protein Edar agonists Edar antagonists hair growth cycle hair growth phase cell death outer root sheath cells genetic removal drug inhibition cell death markers caspase 3 anti-cell death protein Edar activators Edar blockers
Studysummary This study found that Edar signaling plays a role in regulating the hair cycle and apoptosis in hair follicle keratinocytes during the catagen phase in mice.
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