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    Glossary Anti-apoptotic protein

    prevents cells from undergoing programmed cell death

    An anti-apoptotic protein is a type of protein that prevents cells from undergoing apoptosis, which is a form of programmed cell death. These proteins help cells survive under stress or damage by blocking the signals that would normally trigger the cell to self-destruct. This function is crucial in maintaining healthy tissues but can also contribute to diseases like cancer, where cells avoid dying when they should.

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    1. The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function EMBO Reports · 2021 · 10 citations
    2. Autophagy-related protein 12 associates with anti-apoptotic B cell lymphoma-2 to promote apoptosis in gentamicin-induced inner ear hair cell loss Molecular Medicine Reports · 2017 · 2 citations
    3. Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression Stem Cell Research & Therapy · 2021 · 50 citations
    4. Melatonin regulates the mitogen-activated protein kinase ( MAPK ) pathway via the circMPP5-miR-211-MAPK3 axis to induce secondary hair follicle differentiation and development in newborn Cashmere goat kids Research Square (Research Square) · 2022 · 1 citations
    5. Anti-CXCL4 monoclonal antibody accelerates telogen to anagen transition and attenuates apoptosis of the hair follicle in mice Experimental and Therapeutic Medicine · 2017
    6. 502 The stress-responsive secretory protein adrenomedullin 2 potently induces cell cycle arrest and apoptosis in human hair follicles Journal of Investigative Dermatology · 2024
    7. Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen) ˜The œAmerican journal of pathology · 2006 · 43 citations
    8. Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs Cancers · 2019 · 11 citations
    9. Melatonin promotes the development of the secondary hair follicles by regulating circMPP5 Journal of Animal Science and Biotechnology · 2023 · 1 citations
    10. Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix European Journal of Cell Biology · 2017 · 30 citations
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