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    GlossaryUncombable Hair Syndrome

    rare genetic condition causing frizzy, unmanageable hair with unique shaft structure

    Uncombable Hair Syndrome (UHS), also known as Pili Trianguli et Canaliculi or Spun Glass Hair, is a rare genetic condition characterized by dry, frizzy hair that stands out from the scalp and cannot be combed flat. The hair shafts are uniquely structured with a triangular or heart-shaped cross-section and a longitudinal groove, making them resistant to being styled or managed.

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      The Genetics of Hair Shaft Disorders

      research The Genetics of Hair Shaft Disorders

      59 citations, June 2008 in “Journal of The American Academy of Dermatology”
      The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
      Acquired Uncombable Hair Syndrome in a 39-Year-Old Woman

      research Acquired Uncombable Hair Syndrome in a 39-Year-Old Woman

      6 citations, August 1993 in “Archives of Dermatology”
      A woman's hair changed to a dry, tangled texture that's hard to comb after treatment with spironolactone, suggesting the medication might cause such hair changes.
      Uncombable-Hair Syndrome

      research Uncombable-Hair Syndrome

      12 citations, November 1987 in “Pediatric dermatology”
      Four children had unmanageable pale blond hair due to uncombable-hair syndrome.

      research Uncombable Hair Syndrome: A Case Presentation

      February 2013 in “Journal of the American Academy of Dermatology”
      Uncombable hair syndrome causes dry, frizzy hair that can't be combed flat, seen in a young child.
      Deimination In Epidermal Barrier And Hair Formation

      research Deimination In Epidermal Barrier And Hair Formation

      2 citations, October 2023 in “Philosophical transactions - Royal Society. Biological sciences”
      Enzymes that change arginine to citrulline are important for skin barrier and hair formation, and their malfunction can lead to skin conditions and hair disorders.
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      community To anyone starting their hair loss battles. [Sorry for long post]

       6 upvotes 10 years ago
      The user recommends using Regenepure (keto shampoo), Lipogaine (minoxidil), and NatureMade Biotin pills for hair loss treatment and advises against taking finasteride (propecia) without considering potential side effects. They share their own experience with these treatments and suggest reading about both the benefits and risks before deciding on finasteride.