Search

for
Search:

Glossary Uncombable Hair Syndrome

rare genetic condition causing frizzy, unmanageable hair with unique shaft structure

Uncombable Hair Syndrome (UHS), also known as Pili Trianguli et Canaliculi or Spun Glass Hair, is a rare genetic condition characterized by dry, frizzy hair that stands out from the scalp and cannot be combed flat. The hair shafts are uniquely structured with a triangular or heart-shaped cross-section and a longitudinal groove, making them resistant to being styled or managed.

Related Terms

Research

5 / 181 results

research Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome

119 citations , November 2016 in “American journal of human genetics”

This study reports the discovery of mutations in the PADI3, TGM3, and TCHH genes as molecular genetic causes of uncombable hair syndrome in children, indicating an autosomal-recessive inheritance pattern.

research Uncombable hair syndrome: Observations on response to biotin and occurrence in siblings with ectodermal dysplasia

101 citations , July 1985 in “Journal of the American Academy of Dermatology”

In this study, oral biotin improved hair growth, strength, and combability in a child with uncombable hair syndrome, while hair in two others slowly improved without biotin.

research Familial Uncombable Hair Syndrome: Ultrastructural Hair Study and Response to Biotin

49 citations , April 2007 in “Pediatric Dermatology”

This study describes a family with uncombable hair syndrome, suggesting autosomal dominant inheritance, and reports that oral biotin improved hair appearance in two young patients.

research Uncombable-hair Syndrome

12 citations , November 1987 in “Pediatric dermatology”

This report identified longitudinal grooves in the hair shafts of four children, diagnosing them with uncombable-hair syndrome.

research Hair cross-sectioning in uncombable hair syndrome: An easy tool for complex diagnosis

7 citations , June 2018 in “Journal of the American Academy of Dermatology”

This article reviews uncombable hair syndrome, highlighting its symptoms, potential diagnosis methods, and the suggestion for biotin supplements, but it reports no new empirical results.

View more "uncombable hair syndrome" in research →

Community Join

2 / 1000+ results

community Fellas how jealous are we? I would harvest an organ for this set of lettuce.

1680 upvotes 1 year ago

The conversation humorously discusses a person with an unusually thick head of hair, with some users joking about using treatments like Minoxidil and finasteride. Many express envy or disbelief, while others suggest a haircut or comment on facial features.

community Over 95% of his face is covered in hair.

in Satire 349 upvotes 1 year ago

A young man with hypertrichosis has over 95% of his face covered in hair, sparking humorous comments about hair loss treatments like minoxidil and dutasteride. Users joke about transplanting his facial hair and discuss the challenges of his condition compared to typical balding.

View more "uncombable hair syndrome" in community →

Learn

1 / 801 results

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

View more "uncombable hair syndrome" in learn →

Clinics

6 / 500 results

All 500 clinic results →

Experts

1 / 5 results

Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

Related Terms

Hairo Fallas