35 citations
,
January 2006 in “Dermatology Online Journal”
This study observed that finasteride treatment induced mild improvement in androgenetic alopecia in one male patient while stabilizing the condition in another, but lipedematous scalp remained unchanged.
30 citations
,
May 2008 in “International Journal of Dermatology”
This case report describes a 52-year-old black woman with diffuse scalp swelling and thinning hair attributed to a large increase in the thickness of scalp subcutaneous fatty tissue.
28 citations
,
January 2007 in “Journal of dermatology”
This case report describes instances of lipedematous scalp and lipedematousalopecia in white adults, indicating these rare conditions may be more widespread and frequent in this population than previously thought.
9 citations
,
December 2018 in “JAAD case reports”
This study details the characteristics of lipedematousalopecia and lipedematous scalp, two rare scalp conditions, suggesting they may represent different stages of the same disorder, with lipedematous scalp lacking the hair loss seen in lipedematousalopecia.
5 citations
,
January 2019 in “Skin appendage disorders”
This case report emphasizes that lipedematous scalp and lipedematousalopecia are not distinct diseases, highlighting the need to consider reversible causes of alopecia for effective treatment.
Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.
A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.
Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.
Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.
Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.
Got small bald patches they say are from stress? PP405 sprays could help bring them back to life.PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.