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research Application of Histamine Receptors H2R, H3R, and H4R, but Not H1R, in Dermatology

September 2014 in “International Journal of Dermatology and Venereology”

Certain histamine receptors (H2R, H3R, H4R) have unique roles in treating skin diseases, with H2R helping with chronic urticaria and other conditions, H3R providing pain relief and allergy benefits, and H4R reducing inflammation and itchiness.

Repurposing of H1-Receptor Antagonists Cetirizine, Loratadine, and Fexofenadine for Systematic Analysis of ClinicalTrials.gov Trials Using Semi-Automated Processes

research Repurposing of H1-Receptor Antagonists Cetirizine, Loratadine, and Fexofenadine for Systematic Analysis of ClinicalTrials.gov Trials Using Semi-Automated Processes

October 2023 in “Naunyn-Schmiedeberg's Archives of Pharmacology”

Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents

20 citations , June 2022 in “Molecules”

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

research Androgen Antagonists in Androgen Target Tissues

27 citations , January 1984 in “Pharmacology & Therapeutics”

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

research Sex Differences in SARS-CoV-2 Infection Rates and the Potential Link to Prostate Cancer

113 citations , July 2020 in “Communications biology”

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

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community July 1st - Early H2 - Breezula

in Treatment 1 upvotes 4 months ago

Discussion on hair loss treatments, focusing on Breezula, with mentions of Minoxidil, finasteride, RU58841, Pyrilutamide, GT20029, and PP405. Breezula's effectiveness is uncertain, with some trials showing minimal regrowth.

community What has happened to Breezula?

in Research/Science 6 upvotes 1 month ago

Breezula is expected to launch in late 2026, with data being sent to the FDA in early 2026. The process is typical for a successful trial.

community Breezula(CB)Phase3Results Date

in Research/Science 9 upvotes 8 months ago

Breezula's phase 3 results are expected in July or August, with commercialization possibly in two years. There are concerns about delays and effectiveness, and the cost may be high.

community New Breezula Update ( I think)

in Treatment 16 upvotes 3 days ago

Breezula's phase 3 enrollment for hair loss treatment is complete, but results have not been published, causing skepticism about its progress. Some users express doubt about its future, suggesting it may be reserved for exclusive use.

community Possibility of updates or more information on the pp405

in Chat 19 upvotes 4 weeks ago

The conversation discusses the potential updates on the pp405 trial for hair loss, with completion expected by December 2025. Participants express skepticism about new treatments, suggesting continued use of finasteride, while others hope for innovative solutions beyond current medications.

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