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Mannitol diuresis allows higher doses of cis-platinum for testicular cancer treatment without increasing kidney damage.

This study reported that spironolactone at 200 mg/day significantly improved facial hair growth in women with hirsutism and showed a sustained reduction in ovarian androgens over one year.

Caffeine becomes more toxic in rats when food intake is reduced by over 50%.

This article discusses the multifactorial nature of acne vulgaris, detailing its link to androgen-induced sebum production, altered keratinisation, inflammation, and bacterial colonisation, but reports no new research findings.

Spironolactone helps reduce hair growth in women with hirsutism but may cause menstrual irregularities.