research The Evaluation and Treatment of Hirsute Women
This narrative review discusses various causes and treatments of hirsutism in women, emphasizing the importance of identifying androgen-secreting tumors, but does not present new study results.
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5 / 1000+ resultsresearch [G-proteins, receptor signal transduction, and growth hormone secretion].
This review discusses the clinical forms and causes of androgenization in women, as well as therapeutic options, reporting success with antiandrogens like cyproterone acetate and spironolactone for skin symptoms, though results are not permanent.
research An Update of Congenital Adrenal Hyperplasia
This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
research Congenital adrenal hyperplasia
This review discusses the evaluation, clinical presentation, and cutaneous manifestations of congenital adrenal hyperplasia, focusing on differential diagnosis challenges with polycystic ovary syndrome, and reports no new clinical findings.
research Steroidogenesis of the testis – new genes and pathways
This review discusses the pathways of androgen biosynthesis and reports no new findings, highlighting the need to understand the interplay between the classic and backdoor pathways.
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5 / 1000+ resultscommunity My friend is so terrified of balding, he started microdosing estrogen…
A person is microdosing estrogen for hair loss after finasteride and dutasteride failed, risking feminizing effects. Alternatives like minoxidil, RU58841, or hair transplants are suggested.
community Not only balding at a very young age but also not responding to the meds well.
A young person is experiencing aggressive hair loss and not responding well to minoxidil and finasteride. Suggestions include trying dutasteride, hair systems, lifestyle changes, or considering a wig.
community Bile Acid-Mediated DHT Dysregulation Hypothesis
Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.
community Thoughts about ORAL ketoconazole? (pills)
Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.
community DHEA, the culprit behind DUPA ? Read this!
High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.
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