Cardiovascular Risk in Patients With Scarring and Nonscarring Alopecias: Assessing the Current State of Evidence

    September 2023 in “ JEADV Clinical Practice ”
    Rachel Sally, Camille Robinson, Seth Orlow … Kristen Lo Sicco
    Studysummary This study reviewed existing literature and found that androgenic alopecia may be associated with cardiovascular risk factors, while evidence for alopecia areata and cicatricial alopecias is limited and sometimes contradictory.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 51

    1. Frontal Fibrosing Alopecia: A Review of Disease Pathogenesis Frontiers in Medicine · 2022
    2. Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled In Vitro Skin Pharmacology and Physiology · 2021
    3. A Study on the Relationship Between Androgenetic Alopecia and Cardiovascular Risk Using High Sensitivity C-Reactive Protein and Galectin-3 in Men With Early Onset Baldness Biomarkers · 2021
    4. Chemokine C-C Motif Ligand 7 (CCL7), a Biomarker of Atherosclerosis, Is Associated with the Severity of Alopecia Areata: A Preliminary Study Journal of Clinical Medicine · 2021
    5. Association Between Androgenic Alopecia and Coronary Artery Disease: A Cross-Sectional Study of Han Chinese Male Population International Journal of General Medicine · 2021
    6. MTHFR C677T Polymorphism and Serum Homocysteine Level as Risk Factors of Coronary Heart Disease in Patients with Androgenetic Alopecia: A Case-Control Study The American Journal of the Medical Sciences · 2021
    7. Hypertension and Cicatricial Hair Loss: Defining High Value Symptom Clusters Within Reproductive Aging Journal of Dermatology Research and Therapy · 2021
    8. Troponin I in Alopecia Areata and Female Pattern Hair Loss Menoufia Medical Journal · 2021
    9. Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy Journal of the European Academy of Dermatology and Venereology · 2020
    10. Comorbidities in Patients with Lichen Planopilaris: A Retrospective Case-Control Study Journal of The American Academy of Dermatology · 2020
    11. Spironolactone for Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2020
    12. Hair Regrowth in Two Patients with Recalcitrant Central Centrifugal Cicatricial Alopecia After Use of Topical Metformin JAAD Case Reports · 2020
    13. Genome-Wide Association Study in Frontal Fibrosing Alopecia Identifies Four Susceptibility Loci Including HLA-B*07:02 Nature Communications · 2019
    14. Variant PADI3 in Central Centrifugal Cicatricial Alopecia The New England Journal of Medicine · 2019
    15. Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study Skin appendage disorders · 2019
    16. Clinical Profile of Androgenic Alopecia and Its Association with Cardiovascular Risk Factors Indian Journal of Dermatology · 2019
    17. The Medical and Psychosocial Associations of Alopecia: Recognizing Hair Loss as More Than a Cosmetic Concern American Journal of Clinical Dermatology · 2018
    18. Single-Center Analysis of Patients with Frontal Fibrosing Alopecia: Evidence for Hypothyroidism and a Good Quality of Life Journal of international medical research · 2018
    19. Androgenetic Alopecia: Causes, Treatments, and Genetic Factors Elsevier eBooks · 2018
    20. Fibroproliferative Genes Are Preferentially Expressed in Central Centrifugal Cicatricial Alopecia Journal of The American Academy of Dermatology · 2018
    21. Alopecia Areata: A Review of Disease Pathogenesis British journal of dermatology/British journal of dermatology, Supplement · 2018
    22. Medical Comorbidities in Patients with Lichen Planopilaris: A Retrospective Case-Control Study International Journal of Dermatology · 2018
    23. Alopecia Areata Is Associated With Increased Expression of Heart Disease Biomarker Cardiac Troponin I Acta dermato-venereologica · 2018
    24. Androgenetic Alopecia: A Review Endocrine · 2017
    25. PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia PPAR Research · 2017
    26. Lipid Profile in Patients with Androgenetic Alopecia: A Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2016
    27. Cardiovascular Risk in Patients with Alopecia Areata: A Propensity-Matched Retrospective Analysis Journal of the American Academy of Dermatology · 2016
    28. Relationship Between Androgenetic Alopecia and Cardiovascular Risk Factors According to BASP Classification in Koreans Journal of Dermatology · 2016
    29. Lichen Planus and Dyslipidemia: A Systematic Review and Meta-Analysis of Observational Studies International Journal of Dermatology · 2016
    30. Inflammatory Markers and Lp(a) Levels as Cardiovascular Risk Factors in Androgenetic Alopecia Clinical Hemorheology and Microcirculation · 2016
    31. Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2014
    32. Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study Indian Dermatology Online Journal · 2014
    33. Association Between Androgenetic Alopecia and Coronary Artery Disease in Young Male Patients International Journal of Trichology · 2014
    34. Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche The Journal of Pathology · 2013
    35. Association of Androgenetic Alopecia With Mortality From Diabetes Mellitus and Heart Disease JAMA Dermatology · 2013
    36. Androgenetic Alopecia and Risk of Coronary Artery Disease Indian Dermatology Online Journal · 2013
    37. Hair Breakage as a Presenting Sign of Early or Occult Central Centrifugal Cicatricial Alopecia Archives of Dermatology · 2012
    38. Sex Hormone–Binding Globulin and Risk of Hyperglycemia in Patients With Androgenetic Alopecia Journal of The American Academy of Dermatology · 2011
    39. Medical and Environmental Risk Factors for the Development of Central Centrifugal Cicatricial Alopecia Archives of Dermatology · 2011
    40. Androgenetic Alopecia and Insulin Resistance: Are They Truly Associated? International Journal of Dermatology · 2011
    41. Androgenetic Alopecia and Cardiovascular Risk Factors in Men and Women: A Comparative Study Journal of The American Academy of Dermatology · 2010
    42. Association of Androgenetic Alopecia with Metabolic Syndrome in Men: A Community-Based Survey British Journal of Dermatology · 2010
    43. Lichen Planopilaris Treated With a Peroxisome Proliferator-Activated Receptor Gamma Agonist Archives of dermatology · 2009
    44. Androgenic Alopecia and Insulin Resistance: Are They Really Related? Clinical and Experimental Dermatology · 2009
    45. Is Androgenetic Alopecia a Risk for Atherosclerosis? Journal of The European Academy of Dermatology and Venereology · 2009
    46. Androgenetic Alopecia and Insulin Resistance in Young Men Clinical Endocrinology · 2008
    47. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    48. Association of Insulin Resistance Linked Diseases and Hair Loss in Elderly Men: Finnish Population-Based Study Central European Journal of Public Health · 2006
    49. Androgenetic Alopecia and Coronary Artery Disease in Women Dermatology Online Journal · 2005
    50. Early Androgenetic Alopecia as a Marker of Insulin Resistance The Lancet · 2000
    51. Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia Expert Opinion on Investigational Drugs · 1999

    Related research 8

    1. Time to Loss of Response for Dupilumab in Ophiasis-Pattern Alopecia Areata JAAD case reports · 2021
    2. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
    3. A Clinico-Epidemiological Study of Scalp Hair Loss in Children (0–18 Years) in Kota Region, South-East Rajasthan Indian Journal of Dermatology · 2019
    4. Topical and Intralesional Therapies for Alopecia Areata Dermatologic therapy · 2011
    5. Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases Dermatologic Therapy · 2011
    6. Alopecia Areata: Evidence-Based Treatments Seminars in cutaneous medicine and surgery · 2009
    7. Diagnosis of Hair Loss: Clinical Features of Common Causes PubMed · 1992
    8. Diagnosis and Management of the Hair Loss Patient PubMed · 1987