Single-Center Analysis of Patients with Frontal Fibrosing Alopecia: Evidence for Hypothyroidism and a Good Quality of Life

October 2018 in “ Journal of international medical research ”

Eva Maria Valesky, Manuela Denise Maier, Roland Kaufmann, Nadja Zöller, Markus Meißner

frontal fibrosing alopecia hypothyroidism hairline regression atopic disposition quality of life thyroid disease FFA QoL

TLDR Frontal fibrosing alopecia is linked to hypothyroidism but doesn't affect quality of life.

This study analyzed 12 female outpatients with frontal fibrosing alopecia (FFA) over more than 2 years, with a mean age of 70.3 years. It found that FFA was associated with hypothyroidism, but there were no significant effects from any therapies used. Additionally, there was no correlation between hairline regression, disease duration, atopic disposition, and quality of life (QoL). Despite the disease, the overall QoL of the patients was good. The study concluded that the extent of FFA did not impact QoL or atopic predisposition, but there was a strong correlation between FFA and thyroid disease.

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research Alopecia Areata: Overview and Insights from January 2018

290 citations , January 2018 in “Journal of The American Academy of Dermatology”

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

research Frontal Fibrosing Alopecia: Increasing Cases and Treatment Options

6 citations , July 2017 in “British Journal of Dermatology”

Frontal fibrosing alopecia is a scarring hair loss condition mainly affecting older women, with no known cause and treatments that may help stabilize hair loss.

research Frontal Fibrosing Alopecia: A Retrospective Clinical Review of 62 Patients with Treatment Outcome and Long-Term Follow-Up

102 citations , April 2014 in “International Journal of Dermatology”

The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.

research Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients

339 citations , April 2014 in “Journal of The American Academy of Dermatology”

Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.

research Frontal Fibrosing Alopecia: A Clinical Review of 36 Patients

159 citations , November 2010 in “British journal of dermatology/British journal of dermatology, Supplement”

Hydroxychloroquine effectively reduces symptoms of frontal fibrosing alopecia, especially in the first 6 months.

research Post-Menopausal Frontal Fibrosing Alopecia

49 citations , January 2003 in “Clinical and Experimental Dermatology”

The document concludes that post-menopausal frontal fibrosing alopecia is a poorly understood condition that does not respond well to common treatments.